Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_1471Peptidase S41; COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151; KEGG: dat:HRM2_08250 CtpA1; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: C0QJT5 CtpA1; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc). (371 aa)    
Predicted Functional Partners:
Deba_3097
Tetratricopeptide TPR_2 repeat protein; InterProIPR001440:IPR013105:IPR019734:IPR013026:IPR 011990; KEGG: dat:HRM2_20780 tetratricopeptide (TPR) domain protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SPTR: C0QDB3 Tetratricopeptide (TPR) domain protein; PFAM: ChAPs (Chs5p-Arf1p-binding proteins); TIGRFAM: putative PEP-CTERM system TPR-repeat lipoprotein.
  
 
 0.891
Deba_1896
Tetratricopeptide TPR_2 repeat protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterProIPR019734:IPR013105:IPR001440:IPR011717:IPR 013026:IPR011990; KEGG: sfu:Sfum_0074 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; Tetratricopeptide TPR_4; SMART: Tetratricopeptide repeat; SPTR: A0LEC5 TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
   
 
 0.746
Deba_1770
Peptidase M23; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR011055:IPR016047; KEGG: aeh:Mlg_2569 peptidase M23B; PFAM: Peptidase M23; SPTR: Q0A5H8 Peptidase M23B; PFAM: Peptidase family M23.
  
  
 0.630
Deba_1470
KEGG: dat:HRM2_08260 serine/threonine-protein kinase MRCK alpha (CDC42-binding protein kinase alpha); SPTR: C0QJT6 Serine/threonine-protein kinase MRCK alpha (CDC42-binding protein kinase alpha).
       0.628
Deba_2689
Hypothetical protein; InterPro IPR002345:IPR011990; KEGG: sti:Sthe_1174 tetratricopeptide TPR_4; SPTR: D1C2Z3 Tetratricopeptide TPR_4; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
  
 
 0.571
Deba_2353
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR011990:IPR013026:IPR001173:IPR011717; KEGG: sat:SYN_02803 glycosyltransferase; PFAM: glycosyl transferase family 2; Tetratricopeptide TPR_4; SPTR: Q1Q1I3 Putative uncharacterized protein; PFAM: Glycosyl transferase family 2.
  
 
 0.545
Deba_0747
Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR001478:IPR008915; KEGG: dol:Dole_0481 putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: A8ZTM7 Putative membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
 
  
 0.543
Deba_1008
COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterProIPR013105:IPR011717:IPR011990:IPR019734:IPR 013026; KEGG: cbh:CLC_2580 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; SPTR: C6PUP8 Putative uncharacterized protein.
  
 
 0.542
Deba_2035
NLP/P60 protein; InterPro IPR000064; KEGG: sfu:Sfum_0991 NLP/P60 protein; PFAM: NLP/P60 protein; SPTR: A0LGY4 NLP/P60 protein; PFAM: NlpC/P60 family.
    
 
 0.538
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.530
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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