STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_1493COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: dal:Dalk_2022 carboxyl transferase; PFAM: carboxyl transferase; SPTR: B8FG38 Carboxyl transferase; PFAM: Carboxyl transferase domain. (520 aa)    
Predicted Functional Partners:
Deba_3254
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR016185:IPR011054:IPR005481:IPR005479:IPR 005482:IPR011761:IPR011764:IPR013817:IPR013816; KEGG: dol:Dole_2179 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: A8ZUF1 Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-term [...]
 
 0.949
Deba_0880
Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089:IPR011053:IPR001882; KEGG: hoh:Hoch_6688 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: D0LT17 Biotin/lipoyl attachment domain-containing protein; manually curated; PFAM: Biotin-requiring enzyme.
  
 0.918
Deba_3256
Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR011053:IPR000089:IPR001882; KEGG: dol:Dole_2178 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: A8ZUF0 Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme.
 
 0.905
Deba_0690
methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: sfu:Sfum_0455 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A0LFF3 Methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
 
  
 0.775
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.746
Deba_1492
COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136:IPR013785; KEGG: dal:Dalk_0105 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase NPD; SPTR: B8FKK0 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase.
       0.742
Deba_0433
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013785; KEGG: cag:Cagg_1303 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: B8G8E9 Pyruvate carboxyltransferase; PFAM: HMGL-like.
 
 
 0.670
Deba_2144
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
  
  
 0.662
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.644
Deba_3258
InterPro IPR010839; KEGG: dal:Dalk_3171 protein of unknown function DUF1446; PFAM: protein of unknown function DUF1446; SPTR: B8FGF2 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1446).
  
  
 0.607
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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