Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1524COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: dth:DICTH_0761 anti-sigma regulatory factor; PFAM: ATP-binding region ATPase domain protein; SPTR: C1TN97 Anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (151 aa)    
Predicted Functional Partners:
Deba_1525
KEGG: tai:Taci_0690 hypothetical protein; SPTR: D1B9H3 Putative uncharacterized protein; manually curated; PFAM: DRTGG domain.
 
   
 0.950
Deba_1523
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR009016:IPR001450:IPR007202:IPR010766:IPR 017896:IPR017900; KEGG: dat:HRM2_16550 iron-sulfur binding hydrogenase; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; DRTGG domain protein; SPTR: C0QAH8 Iron-sulfur binding hydrogenase; PFAM: Iron only hydrogenase large subunit, C-terminal domain; DRTGG domain; Putative Fe-S cluster; 4Fe-4S binding domain.
   
 0.937
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.936
Deba_1521
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR004358:IPR005467; KEGG: dat:HRM2_16530 sensory signal transduction histidine kinase (ATPase domain protein); PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: B0PGV2 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  
 0.921
Deba_1522
PHP domain protein; COGs: COG1379 conserved hypothetical protein; InterPro IPR003141:IPR016195:IPR004013; KEGG: dth:DICTH_0765 PHP domain, putative; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: A1HP42 PHP C-terminal domain protein; PFAM: PHP domain.
 
   
 0.917
Deba_1520
NAD(P)-dependent iron-only hydrogenase iron-sulfur protein; InterPro IPR012336:IPR012335; KEGG: dat:HRM2_16520 NADP-reducing hydrogenase, subunit B; SPTR: C0QAH5 NADP-reducing hydrogenase, subunit B.
 
     0.868
Deba_2322
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR013325:IPR013324:IPR000943:IPR011991:IPR 007627:IPR007624:IPR007630:IPR014284:IPR012845; KEGG: mgm:Mmc1_3037 FliA/WhiG family RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; SPTR: A0LC35 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; S [...]
  
 
 0.819
Deba_0154
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: swo:Swol_1795 anti-anti-sigma regulatory factor, SpoIIAA; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q0AW11 Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.799
Deba_1234
Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q1NPE5 Sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.799
Deba_2233
Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: hmo:HM1_0319 anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q1NPE5 Sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.799
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.