STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
cobTNicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (351 aa)    
Predicted Functional Partners:
Deba_1529
Adenosylcobinamide-phosphateguanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
  
 0.997
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.987
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.906
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.835
cbiA-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.829
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.709
Deba_2460
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008:IPR000878:IPR006365; KEGG: dvl:Dvul_0558 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: A1VAW5 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (d [...]
 
  
 0.708
Deba_0870
cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
   
 0.697
Deba_0815
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.665
Deba_1099
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR015424:IPR004839:IPR015421; KEGG: gme:Gmet_0487 L-threonine O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Q39YE4 L-threonine O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase.
 
  
 0.660
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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