STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1534COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038; KEGG: tac:Ta0351 acetyl-CoA acetyltransferase; SPTR: Q9HL79 Sterol carrier protein x/sterol carrier protein 2 related protein. (478 aa)    
Predicted Functional Partners:
Deba_0032
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterProIPR001753:IPR006176:IPR008927:IPR016040:IPR 013328; KEGG: hoh:Hoch_3456 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; SPTR: D0LW26 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family.
  
 0.998
Deba_0086
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR001753:IPR006176:IPR006108:IPR016040:IPR 008927:IPR018376:IPR013328; KEGG: 3-hydroxyacyl-CoA dehyrogenase, putative; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: B9RKN5 3-hydroxyacyl-CoA dehyrogenase, putative; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.998
Deba_3133
Short-chain dehydrogenase/reductase SDR; COGs: COG3425 3-hydroxy-3-methylglutaryl CoA synthase; InterProIPR016040:IPR016039:IPR016083:IPR013747:IPR 002878:IPR002198:IPR003033:IPR002347; KEGG: dol:Dole_1550 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; protein of unknown function DUF35; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Sterol-binding domain protein; SPTR: A8ZZV4 Short-chain dehydrogenase/reductase SDR; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C term [...]
 
 
 0.996
Deba_1863
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR017441:IPR006176:IPR006108:IPR001753:IPR 016040:IPR008927:IPR013328; KEGG: chy:CHY_1609 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; SPTR: Q3ABP7 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.993
Deba_1535
Protein of unknown function DUF35; COGs: COG1545 nucleic-acid-binding protein containing a Zn-ribbon; InterPro IPR002878; KEGG: tvo:TVN1259 nucleic-acid-binding protein; PFAM: protein of unknown function DUF35; SPTR: Q978Y2 Putative uncharacterized protein TVG1322512.
 
 
 0.981
Deba_0465
acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR005914:IPR020845; KEGG: noc:Noc_2047 acetoacetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q3J9I9 Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase.
 
 
 0.945
Deba_1491
COGs: COG0372 Citrate synthase; InterProIPR002020:IPR019810:IPR016142:IPR010953:IPR 016141; KEGG: dal:Dalk_4974 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B8FDL5 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 0.937
Deba_0433
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013785; KEGG: cag:Cagg_1303 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: B8G8E9 Pyruvate carboxyltransferase; PFAM: HMGL-like.
  
 
 0.930
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.926
Deba_0943
2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterProIPR013709:IPR000891:IPR002034:IPR013785:IPR 005675; KEGG: sfu:Sfum_2174 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; SPTR: A0LKA4 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family pro [...]
  
 
 0.926
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (12%) [HD]