Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1554COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR003660:IPR003661:IPR003594:IPR 009082:IPR013656:IPR004358:IPR005467; KEGG: dba:Dbac_0336 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: C7LVC1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histidine kinase [...] (610 aa)    
Predicted Functional Partners:
Deba_1553
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR003593:IPR011006:IPR009057:IPR 002078:IPR002197; KEGG: dba:Dbac_0335 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: C7LVC0 Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM [...]
 
 0.957
Deba_1555
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR011006:IPR013105:IPR011990:IPR 019734:IPR013026; KEGG: nth:Nther_0252 response regulator receiver protein; PFAM: response regulator receiver; Tetratricopeptide TPR_2 repeat protein; SMART: response regulator receiver; SPTR: B2A4S9 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 
 0.948
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 
0.873
Deba_1556
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006036; KEGG: kol:Kole_0373 TrkA-N domain protein; PFAM: TrkA-N domain protein; SPTR: B4WH72 TrkA-N domain superfamily; PFAM: TrkA-N domain.
 
   
 0.847
Deba_1557
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037:IPR006036; KEGG: nth:Nther_0254 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: B4WH73 TrkA-N domain family; PFAM: TrkA-N domain; TrkA-C domain.
 
   
 0.844
Deba_1558
Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: kol:Kole_0375 cation transporter; PFAM: cation transporter; SPTR: B4WH74 Cation transport protein; PFAM: Cation transport protein.
 
   
 0.824
Deba_2154
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR011006:IPR001789; KEGG: dal:Dalk_3262 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FJ25 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.723
Deba_2017
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: lip:LI1142 CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q1MP81 CheY-like receiver; PFAM: Response regulator receiver domain.
 
 
 0.697
Deba_1066
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867:IPR018480; KEGG: sfu:Sfum_0707 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: A0LG53 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.654
Deba_0041
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: dal:Dalk_2936 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FKZ1 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.611
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (14%) [HD]