STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1638COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002293; KEGG: ote:Oter_3914 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: B1ZZB6 Amino acid permease-associated region; PFAM: Amino acid permease. (460 aa)    
Predicted Functional Partners:
Deba_0400
Conserved hypothetical protein; InterPro IPR011009:IPR000719; KEGG: dsa:Desal_2316 hypothetical protein; SPTR: C6BWU2 Putative uncharacterized protein.
    
 0.819
Deba_1637
Nickel transport complex, NikM subunit, transmembrane; COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: ppd:Ppro_1251 ABC-type Co2+ transport system periplasmic component-like protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: Q1NY28 ABC-type Co2+ transport system periplasmic component-like; PFAM: Nickel uptake substrate-specific transmembrane region.
 
     0.740
Deba_1636
COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878:IPR014777:IPR014776; KEGG: ppd:Ppro_1250 uroporphyrin-III C/tetrapyrrole methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: A1ANF1 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases.
 
   
 0.658
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
  
 
 0.649
Deba_0318
TrkA-C domain protein; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037:IPR016040; KEGG: dol:Dole_2399 TrkA domain-containing protein; PFAM: TrkA-C domain protein; Citrate transporter; SPTR: A8ZVL6 TrkA-C domain protein; PFAM: TrkA-C domain; Citrate transporter.
  
 
 0.613
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
 
 0.598
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.578
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
 
 
 0.568
Deba_0175
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833:IPR003778:IPR010016; KEGG: sth:STH379 putative allophanate hydrolase; PFAM: Allophanate hydrolase subunit 1; Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 1; Allophanate hydrolase subunit 2; SPTR: Q67SH9 Putative allophanate hydrolase; PFAM: Metallo-beta-lactamase superfamily; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370; biotin-dependent carboxylase uncharacterized domain.
  
  
 0.565
lipB-2
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.556
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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