Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_1651Conserved hypothetical protein; COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dal:Dalk_4908 hypothetical protein; SPTR: B8FDF3 Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). (444 aa)    
Predicted Functional Partners:
Deba_2873
Amine oxidase; COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR002937; KEGG: gsu:GSU1512 amine oxidase, flavin-containing; PFAM: amine oxidase; SPTR: Q74D07 Amine oxidase, flavin-containing; PFAM: Flavin containing amine oxidoreductase.
  
  
 0.889
Deba_1648
InterPro IPR012437; KEGG: dal:Dalk_4914 protein of unknown function DUF1638; PFAM: Protein of unknown function DUF1638; SPTR: B8FDF9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638).
 
   
 0.884
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.880
Deba_1650
COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4909 methionine synthase; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF4 Methionine synthase; PFAM: B12 binding domain.
 
  
 0.834
Deba_2958
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: dol:Dole_1224 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: A8ZY23 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.774
Deba_1649
Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4910 methionine synthase; PFAM: dihydropteroate synthase DHPS; SPTR: B8FDF5 Methionine synthase; PFAM: Pterin binding enzyme.
 
  
 0.760
Deba_2983
Hypothetical protein; InterPro IPR011031; KEGG: sat:SYN_02638 iron-sulphur-binding reductase; SPTR: C8QXC7 Cytochrome C family protein; TIGRFAM: doubled CXXCH domain.
  
   
 0.715
Deba_1152
COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.694
Deba_1646
COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4912 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF7 Cobalamin B12-binding domain protein; PFAM: B12 binding domain.
 
  
 0.688
Deba_1653
Ferredoxin; COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041:IPR012675; KEGG: mta:Moth_2112 ferredoxin; PFAM: ferredoxin; SPTR: Q2RGN5 Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
 
  
 0.678
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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