| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Deba_0815 | Deba_1152 | Deba_0815 | Deba_1152 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.441 |
| Deba_0815 | Deba_1290 | Deba_0815 | Deba_1290 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | 0.698 |
| Deba_0815 | Deba_1651 | Deba_0815 | Deba_1651 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Conserved hypothetical protein; COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dal:Dalk_4908 hypothetical protein; SPTR: B8FDF3 Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.671 |
| Deba_0815 | Deba_2873 | Deba_0815 | Deba_2873 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Amine oxidase; COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR002937; KEGG: gsu:GSU1512 amine oxidase, flavin-containing; PFAM: amine oxidase; SPTR: Q74D07 Amine oxidase, flavin-containing; PFAM: Flavin containing amine oxidoreductase. | 0.676 |
| Deba_0815 | Deba_2983 | Deba_0815 | Deba_2983 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Hypothetical protein; InterPro IPR011031; KEGG: sat:SYN_02638 iron-sulphur-binding reductase; SPTR: C8QXC7 Cytochrome C family protein; TIGRFAM: doubled CXXCH domain. | 0.416 |
| Deba_0815 | hemC | Deba_0815 | Deba_0814 | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| Deba_1152 | Deba_0815 | Deba_1152 | Deba_0815 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.441 |
| Deba_1152 | Deba_1290 | Deba_1152 | Deba_1290 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | 0.739 |
| Deba_1152 | Deba_1651 | Deba_1152 | Deba_1651 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | Conserved hypothetical protein; COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dal:Dalk_4908 hypothetical protein; SPTR: B8FDF3 Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.696 |
| Deba_1290 | Deba_0815 | Deba_1290 | Deba_0815 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.698 |
| Deba_1290 | Deba_1152 | Deba_1290 | Deba_1152 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.739 |
| Deba_1290 | Deba_1651 | Deba_1290 | Deba_1651 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | Conserved hypothetical protein; COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dal:Dalk_4908 hypothetical protein; SPTR: B8FDF3 Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.679 |
| Deba_1290 | hemC | Deba_1290 | Deba_0814 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.458 |
| Deba_1646 | Deba_1648 | Deba_1646 | Deba_1648 | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4912 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF7 Cobalamin B12-binding domain protein; PFAM: B12 binding domain. | InterPro IPR012437; KEGG: dal:Dalk_4914 protein of unknown function DUF1638; PFAM: Protein of unknown function DUF1638; SPTR: B8FDF9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | 0.683 |
| Deba_1646 | Deba_1649 | Deba_1646 | Deba_1649 | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4912 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF7 Cobalamin B12-binding domain protein; PFAM: B12 binding domain. | Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4910 methionine synthase; PFAM: dihydropteroate synthase DHPS; SPTR: B8FDF5 Methionine synthase; PFAM: Pterin binding enzyme. | 0.987 |
| Deba_1646 | Deba_1650 | Deba_1646 | Deba_1650 | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4912 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF7 Cobalamin B12-binding domain protein; PFAM: B12 binding domain. | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4909 methionine synthase; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF4 Methionine synthase; PFAM: B12 binding domain. | 0.435 |
| Deba_1646 | Deba_1651 | Deba_1646 | Deba_1651 | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4912 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF7 Cobalamin B12-binding domain protein; PFAM: B12 binding domain. | Conserved hypothetical protein; COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dal:Dalk_4908 hypothetical protein; SPTR: B8FDF3 Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.701 |
| Deba_1648 | Deba_1646 | Deba_1648 | Deba_1646 | InterPro IPR012437; KEGG: dal:Dalk_4914 protein of unknown function DUF1638; PFAM: Protein of unknown function DUF1638; SPTR: B8FDF9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4912 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF7 Cobalamin B12-binding domain protein; PFAM: B12 binding domain. | 0.683 |
| Deba_1648 | Deba_1649 | Deba_1648 | Deba_1649 | InterPro IPR012437; KEGG: dal:Dalk_4914 protein of unknown function DUF1638; PFAM: Protein of unknown function DUF1638; SPTR: B8FDF9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4910 methionine synthase; PFAM: dihydropteroate synthase DHPS; SPTR: B8FDF5 Methionine synthase; PFAM: Pterin binding enzyme. | 0.847 |
| Deba_1648 | Deba_1650 | Deba_1648 | Deba_1650 | InterPro IPR012437; KEGG: dal:Dalk_4914 protein of unknown function DUF1638; PFAM: Protein of unknown function DUF1638; SPTR: B8FDF9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: dal:Dalk_4909 methionine synthase; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: B8FDF4 Methionine synthase; PFAM: B12 binding domain. | 0.818 |