STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1657Metal dependent phosphohydrolase; COGs: COG1203 helicase; InterProIPR006675:IPR006474:IPR014001:IPR006674:IPR 014021; KEGG: dvm:DvMF_1971 CRISPR-associated helicase Cas3; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: DEAD-like helicase; SPTR: B8DQ50 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; metal dependent phophohydrolase; PFAM: HD domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; uncharacterized domain HDIG. (741 aa)    
Predicted Functional Partners:
Deba_1661
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
  
 0.943
Deba_1660
CRISPR-associated protein, Csd2 family; COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482:IPR013418; KEGG: cvi:CV_1227 hypothetical protein; PFAM: CRISPR-associated protein TM1801; SPTR: C0GMN1 CRISPR-associated protein, Csd2 family; TIGRFAM: CRISPR-associated protein, Csd2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family.
 
  
 0.935
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.932
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.930
Deba_1658
InterPro IPR013422:IPR010155; KEGG: mfa:Mfla_0602 CRISPR-associated Cas5d family protein; PFAM: CRISPR-associated protein CT1134; SPTR: C0GMN3 CRISPR-associated protein Cas5 family; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Dvulg subtype; CRISPR-associated protein Cas5, N-terminal domain.
 
   
 0.924
Deba_1659
CRISPR-associated protein, Csd1 family; InterPro IPR010144; KEGG: dma:DMR_14370 hypothetical protein; PFAM: CRISPR-associated protein CT1133; SPTR: C4XNF3 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein, Csd1 family.
 
   
 0.923
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.642
Deba_1152
COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.476
Deba_1209
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SMART: CBS domain containing protein; SPTR: A0LG26 Polynucleotide adenylyltransferase region; PFAM: DHH family; DHHA1 domain; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.471
Deba_0352
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.466
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.