Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Deba_1677Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001808:IPR018490:IPR014710:IPR 011991:IPR012318; KEGG: dal:Dalk_0952 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: B8FI88 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (232 aa)    
Predicted Functional Partners:
Deba_3298
Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: sfu:Sfum_2382 adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: A0LKW1 Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain.
  
 0.833
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.820
Deba_0963
TPR repeat-containing protein; InterPro IPR001440:IPR011990:IPR019734:IPR013026; KEGG: ami:Amir_6259 NB-ARC domain protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: C6WIY7 NB-ARC domain protein; PFAM: Tetratricopeptide repeat.
  
 0.808
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.807
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.806
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.795
Deba_1392
Response regulator receiver protein; InterProIPR001789:IPR001440:IPR013105:IPR019734:IPR 013026:IPR011990:IPR006597:IPR011006; KEGG: dat:HRM2_46700 TPR-repeat-containing protein with CheY-like receiver; PFAM: response regulator receiver; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: response regulator receiver; Tetratricopeptide repeat; Sel1 domain protein repeat-containing protein; SPTR: C0QGE7 TPR-repeat-containing protein with CheY-like receiver; PFAM: Response regulator receiver domain; Tetratricopeptide repeat.
  
 
 0.794
Deba_1897
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.747
rpoD
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.735
Deba_3269
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.735
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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