STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1677Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001808:IPR018490:IPR014710:IPR 011991:IPR012318; KEGG: dal:Dalk_0952 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: B8FI88 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (232 aa)    
Predicted Functional Partners:
Deba_1392
Response regulator receiver protein; InterProIPR001789:IPR001440:IPR013105:IPR019734:IPR 013026:IPR011990:IPR006597:IPR011006; KEGG: dat:HRM2_46700 TPR-repeat-containing protein with CheY-like receiver; PFAM: response regulator receiver; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: response regulator receiver; Tetratricopeptide repeat; Sel1 domain protein repeat-containing protein; SPTR: C0QGE7 TPR-repeat-containing protein with CheY-like receiver; PFAM: Response regulator receiver domain; Tetratricopeptide repeat.
  
 
 0.862
Deba_3298
Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: sfu:Sfum_2382 adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: A0LKW1 Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain.
  
 0.830
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.779
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.776
Deba_0963
TPR repeat-containing protein; InterPro IPR001440:IPR011990:IPR019734:IPR013026; KEGG: ami:Amir_6259 NB-ARC domain protein; PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: C6WIY7 NB-ARC domain protein; PFAM: Tetratricopeptide repeat.
  
 0.767
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.760
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.751
Deba_0423
COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dol:Dole_1493 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: A8ZZE4 Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
    
  0.744
Deba_0507
Diguanylate cyclase and serine/threonine protein kinase with TPR repeats; InterProIPR000160:IPR001440:IPR013105:IPR006597:IPR 011717:IPR019734:IPR011990:IPR013026; KEGG: drt:Dret_2188 diguanylate cyclase and serine/threonine protein kinase with TPR repeats; PFAM: Tetratricopeptide TPR_2 repeat protein; GGDEF domain containing protein; TPR repeat-containing protein; Sel1 domain protein repeat-containing protein; Tetratricopeptide TPR_4; SMART: GGDEF domain containing protein; Tetratricopeptide repeat; SPTR: C8X4X5 Diguanylate cyclase and serine/threonine protein kinase with TPR repeats; [...]
   
 
 0.723
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
 
 0.685
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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