STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1-2CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (655 aa)    
Predicted Functional Partners:
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.997
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.988
Deba_0257
Methyltransferase FkbM family; InterPro IPR006342; KEGG: mlb:MLBr_02346 hypothetical protein; SPTR: B9YTU9 Methyltransferase FkbM family; TIGRFAM: methyltransferase FkbM family; TIGRFAM: methyltransferase, FkbM family.
  
 
 0.985
Deba_1693
KEGG: dau:Daud_1295 hypothetical protein; SPTR: A4BL60 Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2276).
 
  
 0.889
Deba_1661
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 0.867
Deba_1657
Metal dependent phosphohydrolase; COGs: COG1203 helicase; InterProIPR006675:IPR006474:IPR014001:IPR006674:IPR 014021; KEGG: dvm:DvMF_1971 CRISPR-associated helicase Cas3; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: DEAD-like helicase; SPTR: B8DQ50 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; metal dependent phophohydrolase; PFAM: HD domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; uncharacterized domain HDIG.
 
  
 0.642
Deba_1352
Protein of unknown function DUF324; InterPro IPR005537; KEGG: syn:sll7066 hypothetical protein; PFAM: protein of unknown function DUF324; SPTR: Q6ZED2 Putative uncharacterized protein sll7066; PFAM: RAMP superfamily.
 
     0.605
Deba_1351
KEGG: syn:sll7067 hypothetical protein; SPTR: Q6ZED1 Putative uncharacterized protein sll7067.
 
  
 0.543
Deba_1355
Protein of unknown function DUF324; InterPro IPR005537; KEGG: syn:sll7063 hypothetical protein; PFAM: protein of unknown function DUF324; SPTR: B5WA38 Putative uncharacterized protein; PFAM: RAMP superfamily.
 
   
 0.541
Deba_1950
Transcriptional regulator, XRE family; InterPro IPR001387:IPR013096:IPR011051:IPR014710; KEGG: drt:Dret_1668 transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: C8X3F5 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix.
   
 
 0.534
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.