Deba_1727 protein (Desulfarculus baarsii) - STRING interaction network

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Deba_1727

Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (463 aa)

Predicted Functional Partners:

dnaG

0.946

rplI

0.902

dnaA

0.885

dnaA-2

0.883

Deba_1830

0.828

hflX

0.824

Deba_0111

0.780

Deba_1720

0.780

Deba_2241

0.780

topA

0.757

Your Current Organism:

Desulfarculus baarsii

NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Deba_0111	Deba_1727	Deba_0111	Deba_1727	Hypothetical protein; KEGG: eic:NT01EI_1130 outer membrane usher protein FimD, putative; SPTR: B8A6Z1 Putative uncharacterized protein.	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	0.780
Deba_0111	rplI	Deba_0111	Deba_1728	Hypothetical protein; KEGG: eic:NT01EI_1130 outer membrane usher protein FimD, putative; SPTR: B8A6Z1 Putative uncharacterized protein.	Ribosomal protein L9; Binds to the 23S rRNA.	0.512
Deba_0111	topA	Deba_0111	Deba_1132	Hypothetical protein; KEGG: eic:NT01EI_1130 outer membrane usher protein FimD, putative; SPTR: B8A6Z1 Putative uncharacterized protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.653
Deba_1720	Deba_1727	Deba_1720	Deba_1727	Bifunctional DNA primase/polymerase; InterPro IPR015330:IPR000276; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	0.780
Deba_1720	rplI	Deba_1720	Deba_1728	Bifunctional DNA primase/polymerase; InterPro IPR015330:IPR000276; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.	Ribosomal protein L9; Binds to the 23S rRNA.	0.512
Deba_1720	topA	Deba_1720	Deba_1132	Bifunctional DNA primase/polymerase; InterPro IPR015330:IPR000276; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.653
Deba_1727	Deba_0111	Deba_1727	Deba_0111	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	Hypothetical protein; KEGG: eic:NT01EI_1130 outer membrane usher protein FimD, putative; SPTR: B8A6Z1 Putative uncharacterized protein.	0.780
Deba_1727	Deba_1720	Deba_1727	Deba_1720	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	Bifunctional DNA primase/polymerase; InterPro IPR015330:IPR000276; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.	0.780
Deba_1727	Deba_1830	Deba_1727	Deba_1830	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	DNA primase catalytic core domain protein; COGs: COG0358 DNA primase; InterPro IPR002694:IPR013264; KEGG: sfu:Sfum_3790 DNA primase catalytic core; PFAM: DNA primase catalytic core domain; SMART: zinc finger CHC2-family protein; SPTR: A0LPV7 DNA primase catalytic core, N-terminal domain; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.	0.828
Deba_1727	Deba_2241	Deba_1727	Deba_2241	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	Bifunctional DNA primase/polymerase; InterPro IPR015330; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.	0.780
Deba_1727	dnaA	Deba_1727	Deba_0001	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.885
Deba_1727	dnaA-2	Deba_1727	Deba_0245	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.883
Deba_1727	dnaG	Deba_1727	Deba_1280	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.946
Deba_1727	hflX	Deba_1727	Deba_1726	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.	0.824
Deba_1727	rplI	Deba_1727	Deba_1728	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	Ribosomal protein L9; Binds to the 23S rRNA.	0.902
Deba_1727	topA	Deba_1727	Deba_1132	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.757
Deba_1830	Deba_1727	Deba_1830	Deba_1727	DNA primase catalytic core domain protein; COGs: COG0358 DNA primase; InterPro IPR002694:IPR013264; KEGG: sfu:Sfum_3790 DNA primase catalytic core; PFAM: DNA primase catalytic core domain; SMART: zinc finger CHC2-family protein; SPTR: A0LPV7 DNA primase catalytic core, N-terminal domain; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	0.828
Deba_1830	dnaG	Deba_1830	Deba_1280	DNA primase catalytic core domain protein; COGs: COG0358 DNA primase; InterPro IPR002694:IPR013264; KEGG: sfu:Sfum_3790 DNA primase catalytic core; PFAM: DNA primase catalytic core domain; SMART: zinc finger CHC2-family protein; SPTR: A0LPV7 DNA primase catalytic core, N-terminal domain; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.900
Deba_1830	topA	Deba_1830	Deba_1132	DNA primase catalytic core domain protein; COGs: COG0358 DNA primase; InterPro IPR002694:IPR013264; KEGG: sfu:Sfum_3790 DNA primase catalytic core; PFAM: DNA primase catalytic core domain; SMART: zinc finger CHC2-family protein; SPTR: A0LPV7 DNA primase catalytic core, N-terminal domain; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.511
Deba_2241	Deba_1727	Deba_2241	Deba_1727	Bifunctional DNA primase/polymerase; InterPro IPR015330; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.	Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.	0.780

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