STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1733RNA modification enzyme, MiaB family; COGs: COG0621 2-methylthioadenine synthetase; InterPro IPR005839:IPR006638:IPR013848:IPR007197; KEGG: sfu:Sfum_0166 RNA modification protein; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: A0LEL6 RNA modification enzyme, MiaB family; TIGRFAM: RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: RNA modification enzyme, MiaB family. (428 aa)    
Predicted Functional Partners:
Deba_1734
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR015421:IPR015422:IPR 001176:IPR004838; KEGG: dal:Dalk_0567 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: B8FHI5 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
 
   
 0.833
Deba_0352
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.712
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.626
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
  
 0.541
Deba_1731
NUDIX hydrolase; InterPro IPR015797:IPR000086; KEGG: mav:MAV_1301 hydrolase, NUDIX family protein; PFAM: NUDIX hydrolase; SPTR: A0QCA8 Hydrolase, NUDIX family protein; PFAM: NUDIX domain.
  
    0.522
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
   0.517
Deba_1732
TPR repeat-containing protein; InterPro IPR019734:IPR001440:IPR011990:IPR013026; KEGG: sfu:Sfum_0684 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SPTR: A0LG31 Tetratricopeptide TPR_2 repeat protein.
       0.511
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.494
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
  
 0.486
Deba_1735
KEGG: sfu:Sfum_2838 hypothetical protein; SPTR: A0LM64 Conserved hypothetical cytosolic protein.
       0.473
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.