STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_1749Response regulator receiver sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR001789:IPR003661:IPR003594:IPR011006:IPR 009082:IPR004358:IPR005467; KEGG: ote:Oter_3856 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: B1ZZ58 Sensor protein; PFAM: Response regulator receiver d [...] (367 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 
0.959
Deba_1750
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006; KEGG: mpd:MCP_2581 putative response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FJ25 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.955
Deba_1160
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR011006:IPR009082:IPR 011620:IPR013655:IPR013656:IPR013767:IPR003661:IPR001789:I PR005467:IPR000014:IPR000700:IPR001610; KEGG: cyn:Cyan7425_3579 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein [...]
 
 
0.920
Deba_0862
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000700:IPR011006:IPR009082:IPR004358:I PR013767:IPR000169; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: A0LKY0 Sensor p [...]
 
 
0.915
Deba_2017
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: lip:LI1142 CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q1MP81 CheY-like receiver; PFAM: Response regulator receiver domain.
 
 
 0.893
Deba_2154
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR011006:IPR001789; KEGG: dal:Dalk_3262 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FJ25 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.888
Deba_0630
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR011006:IPR009082:IPR004358:IPR013656:I PR013767; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; re [...]
 
 
0.868
Deba_2845
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003661:IPR003594:IPR000014:IPR 005467:IPR004358:IPR009082; KEGG: gsu:GSU1038 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q74EC5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His [...]
 
 
 0.858
Deba_0403
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR003661:IPR 003594:IPR011006:IPR009082:IPR000014:IPR001610:IPR004358:I PR005467:IPR000700; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region [...]
 
 
0.857
Deba_0349
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003661:IPR003594:IPR009082:IPR 000014:IPR004358:IPR005467; KEGG: sfu:Sfum_2495 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: A0LL72 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-l [...]
 
 
 0.855
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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