| node1 | node2 | node1 annotation | node2 annotation | score |
| Deba_0021 | Deba_1773 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR000731:IPR004764; KEGG: dde:Dde_0401 hydrophobe/amphiphile efflux-1 HAE1; PFAM: acriflavin resistance protein; SPTR: Q316E4 Hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | 0.645 |
| Deba_0021 | Deba_1805 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR000731:IPR004764; KEGG: dde:Dde_0401 hydrophobe/amphiphile efflux-1 HAE1; PFAM: acriflavin resistance protein; SPTR: Q316E4 Hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_00680 HlyD; PFAM: secretion protein HlyD family protein; SPTR: Q1JW26 Secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.599 |
| Deba_0021 | Deba_1809 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR000731:IPR004764; KEGG: dde:Dde_0401 hydrophobe/amphiphile efflux-1 HAE1; PFAM: acriflavin resistance protein; SPTR: Q316E4 Hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | RND efflux system, outer membrane lipoprotein, NodT family; COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: dat:HRM2_00710 proton-shuffling outer membrane efflux protein (OprM-like); PFAM: outer membrane efflux protein; SPTR: Q1JW30 RND efflux system, outer membrane lipoprotein, NodT; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. | 0.604 |
| Deba_0624 | Deba_1773 | Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: hoh:Hoch_6213 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: D0LMK0 Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | 0.626 |
| Deba_0624 | Deba_1805 | Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: hoh:Hoch_6213 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: D0LMK0 Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_00680 HlyD; PFAM: secretion protein HlyD family protein; SPTR: Q1JW26 Secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.599 |
| Deba_0624 | Deba_1809 | Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: hoh:Hoch_6213 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: D0LMK0 Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | RND efflux system, outer membrane lipoprotein, NodT family; COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: dat:HRM2_00710 proton-shuffling outer membrane efflux protein (OprM-like); PFAM: outer membrane efflux protein; SPTR: Q1JW30 RND efflux system, outer membrane lipoprotein, NodT; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. | 0.482 |
| Deba_1643 | Deba_1773 | Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: protein of unknown function DUF214; SPTR: A0LM36 Macrolide export ATP-binding/permease protein macB; PFAM: Predicted permease. | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | 0.658 |
| Deba_1643 | Deba_1805 | Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: protein of unknown function DUF214; SPTR: A0LM36 Macrolide export ATP-binding/permease protein macB; PFAM: Predicted permease. | Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_00680 HlyD; PFAM: secretion protein HlyD family protein; SPTR: Q1JW26 Secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.760 |
| Deba_1643 | Deba_1807 | Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: protein of unknown function DUF214; SPTR: A0LM36 Macrolide export ATP-binding/permease protein macB; PFAM: Predicted permease. | ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: dat:HRM2_00700 ABC-type transporter, predicted ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q1K3J3 ABC transporter related; PFAM: ABC transporter. | 0.987 |
| Deba_1643 | Deba_1809 | Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: protein of unknown function DUF214; SPTR: A0LM36 Macrolide export ATP-binding/permease protein macB; PFAM: Predicted permease. | RND efflux system, outer membrane lipoprotein, NodT family; COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: dat:HRM2_00710 proton-shuffling outer membrane efflux protein (OprM-like); PFAM: outer membrane efflux protein; SPTR: Q1JW30 RND efflux system, outer membrane lipoprotein, NodT; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. | 0.588 |
| Deba_1773 | Deba_0021 | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR000731:IPR004764; KEGG: dde:Dde_0401 hydrophobe/amphiphile efflux-1 HAE1; PFAM: acriflavin resistance protein; SPTR: Q316E4 Hydrophobe/amphiphile efflux-1 HAE1; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | 0.645 |
| Deba_1773 | Deba_0624 | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: hoh:Hoch_6213 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: D0LMK0 Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.626 |
| Deba_1773 | Deba_1643 | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: protein of unknown function DUF214; SPTR: A0LM36 Macrolide export ATP-binding/permease protein macB; PFAM: Predicted permease. | 0.658 |
| Deba_1773 | Deba_1784 | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR004764:IPR001036; KEGG: lhk:LHK_02130 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; SPTR: C1D9L2 Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | 0.952 |
| Deba_1773 | Deba_1805 | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_00680 HlyD; PFAM: secretion protein HlyD family protein; SPTR: Q1JW26 Secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.634 |
| Deba_1784 | Deba_1773 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR004764:IPR001036; KEGG: lhk:LHK_02130 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; SPTR: C1D9L2 Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. | 0.952 |
| Deba_1784 | Deba_1805 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR004764:IPR001036; KEGG: lhk:LHK_02130 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; SPTR: C1D9L2 Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_00680 HlyD; PFAM: secretion protein HlyD family protein; SPTR: Q1JW26 Secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.599 |
| Deba_1784 | Deba_1809 | Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR004764:IPR001036; KEGG: lhk:LHK_02130 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; SPTR: C1D9L2 Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. | RND efflux system, outer membrane lipoprotein, NodT family; COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: dat:HRM2_00710 proton-shuffling outer membrane efflux protein (OprM-like); PFAM: outer membrane efflux protein; SPTR: Q1JW30 RND efflux system, outer membrane lipoprotein, NodT; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. | 0.632 |
| Deba_1804 | Deba_1805 | Transcriptional regulator, TetR family; InterPro IPR011075:IPR009057:IPR001647:IPR015893; KEGG: dat:HRM2_00670 HTH-type transcriptional regulator (TetR-family protein); PFAM: regulatory protein TetR; SPTR: Q2N4Y3 Transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family; YsiA-like protein, C-terminal region. | Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_00680 HlyD; PFAM: secretion protein HlyD family protein; SPTR: Q1JW26 Secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.952 |
| Deba_1804 | Deba_1806 | Transcriptional regulator, TetR family; InterPro IPR011075:IPR009057:IPR001647:IPR015893; KEGG: dat:HRM2_00670 HTH-type transcriptional regulator (TetR-family protein); PFAM: regulatory protein TetR; SPTR: Q2N4Y3 Transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family; YsiA-like protein, C-terminal region. | Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dat:HRM2_00690 ABC-type transporter, predicted premease protein; PFAM: protein of unknown function DUF214; SPTR: Q1JW27 Putative uncharacterized protein; manually curated; PFAM: Predicted permease. | 0.953 |