| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Deba_0572 | Deba_1163 | Deba_0572 | Deba_1163 | Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mrd:Mrad2831_2432 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B1LZ06 Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | 0.932 |
| Deba_0572 | dapF | Deba_0572 | Deba_1877 | Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mrd:Mrad2831_2432 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B1LZ06 Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.919 |
| Deba_0572 | dapL | Deba_0572 | Deba_1873 | Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mrd:Mrad2831_2432 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B1LZ06 Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.911 |
| Deba_1152 | Deba_1874 | Deba_1152 | Deba_1874 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | 0.495 |
| Deba_1152 | dapF | Deba_1152 | Deba_1877 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.755 |
| Deba_1152 | dapL | Deba_1152 | Deba_1873 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.528 |
| Deba_1152 | murE | Deba_1152 | Deba_2788 | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.498 |
| Deba_1163 | Deba_0572 | Deba_1163 | Deba_0572 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mrd:Mrad2831_2432 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B1LZ06 Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | 0.932 |
| Deba_1163 | dapA | Deba_1163 | Deba_1876 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.412 |
| Deba_1163 | dapB | Deba_1163 | Deba_1875 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.481 |
| Deba_1163 | dapF | Deba_1163 | Deba_1877 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.939 |
| Deba_1163 | dapL | Deba_1163 | Deba_1873 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.916 |
| Deba_1163 | lysA | Deba_1163 | Deba_1878 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.412 |
| Deba_1548 | dapF | Deba_1548 | Deba_1877 | Putative phytochrome sensor protein; InterPro IPR003018; KEGG: dol:Dole_1615 response regulator receiver protein; PFAM: GAF domain protein; SPTR: A9A019 Response regulator receiver protein; PFAM: Protein of unknown function, DUF484. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.822 |
| Deba_1874 | Deba_1152 | Deba_1874 | Deba_1152 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.495 |
| Deba_1874 | dapA | Deba_1874 | Deba_1876 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.828 |
| Deba_1874 | dapB | Deba_1874 | Deba_1875 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.818 |
| Deba_1874 | dapF | Deba_1874 | Deba_1877 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.760 |
| Deba_1874 | dapL | Deba_1874 | Deba_1873 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.807 |
| Deba_1874 | lysA | Deba_1874 | Deba_1878 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.781 |