STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
Deba_1890Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284:IPR001453:IPR020817; KEGG: sfu:Sfum_0070 molybdenum cofactor synthesis domain-containing protein; PFAM: molybdopterin binding domain; SPTR: A0LEC1 Molybdopterin adenylyltransferase; TIGRFAM: molybdenum cofactor synthesis domain protein; manually curated; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (163 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.995
Deba_0760
MOSC domain containing protein; COGs: COG2258 conserved hypothetical protein; InterPro IPR005302:IPR015808:IPR011037; KEGG: ppd:Ppro_0303 MOSC domain-containing protein; PFAM: MOSC domain containing protein; SPTR: A1AKR7 MOSC domain containing protein; PFAM: MOSC domain.
   
 0.969
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.891
Deba_1889
COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 020568:IPR009000:IPR009022:IPR014721:IPR004540:IPR005225; KEGG: sfu:Sfum_0068 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain protein; SPTR: A0LEB9 Translation elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation [...]
     
 0.798
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
 
      0.744
Deba_0703
Molybdopterin binding domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.697
Deba_1891
Conserved hypothetical protein; COGs: COG1661 DNA-binding protein with PD1-like DNA-binding motif; KEGG: dma:DMR_35880 hypothetical protein; SPTR: C4XLE0 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF296).
       0.596
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.530
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.490
Deba_1888
Methyltransferase type 12; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013217; KEGG: npu:Npun_F0952 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: B2IUB2 Methyltransferase type 11; PFAM: Methyltransferase domain.
       0.480
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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