STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_1920AAA ATPase central domain protein; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: dol:Dole_2133 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: A8ZU04 AAA ATPase central domain protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA). (452 aa)    
Predicted Functional Partners:
Deba_0246
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.816
Deba_1921
Patatin; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641:IPR016035; KEGG: sfu:Sfum_1691 patatin; PFAM: Patatin; SPTR: A0LIX6 Patatin; PFAM: Patatin-like phospholipase.
       0.788
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.730
Deba_2640
Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: mta:Moth_0135 Appr-1-p processing; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: A0A021 Putative uncharacterized protein; PFAM: Macro domain.
  
   0.721
Deba_1143
Competence/damage-inducible protein CinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: gme:Gmet_0196 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: C8QYB6 Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybden [...]
     
 0.643
Deba_2577
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 
 0.636
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
   0.568
rpsU
Ribosomal protein S21; InterPro IPR018278:IPR001911; KEGG: pca:Pcar_2255 30S ribosomal protein S21; SPTR: Q1JW03 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; manually curated; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
       0.534
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.533
Deba_2695
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR016055:IPR005844:IPR005845:IPR 005846:IPR005843:IPR005841; KEGG: sfu:Sfum_0481 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; SPTR: A0LFH9 Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...]
  
   0.513
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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