Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_1939COGs: COG3830 ACT domain-containing protein; InterPro IPR002912; KEGG: mvu:Metvu_1156 ACT domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: C9RHG2 ACT domain-containing protein; PFAM: ACT domain. (92 aa)    
Predicted Functional Partners:
Deba_1938
Protein of unknown function DUF711; COGs: COG2848 conserved hypothetical protein; InterPro IPR007841; KEGG: adg:Adeg_1269 protein of unknown function DUF711; PFAM: protein of unknown function DUF711; SPTR: C9R7V0 Putative uncharacterized protein; PFAM: Uncharacterized ACR (DUF711).
 
     0.954
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.792
Deba_1941
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.791
Deba_3024
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: dal:Dalk_2782 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: B8FKV2 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
   
 0.646
Deba_1942
Methyl-accepting chemotaxis sensory transducer with Cache sensor; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004090:IPR003660:IPR004089:IPR013163; KEGG: gme:Gmet_1078 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Q39WQ6 Methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
       0.538
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
       0.439
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.412
Deba_0210
COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011095:IPR011761:IPR013816; KEGG: sfu:Sfum_0713 D-alanine--D-alanine ligase domain-containing protein; PFAM: D-alanine--D-alanine ligase domain protein; SPTR: A0LG59 D-alanine--D-alanine ligase domain protein; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase.
  
    0.406
Deba_0211
COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011095:IPR011761:IPR013816; KEGG: sfu:Sfum_0712 D-alanine--D-alanine ligase domain-containing protein; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: A0LG58 D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase.
  
    0.406
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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