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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (232 aa)    
Predicted Functional Partners:
Deba_2285
COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR004808:IPR000097; KEGG: sfu:Sfum_2331 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: A0LKR0 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
 
 0.991
rnfE
Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.931
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
 
 0.875
Deba_1938
Protein of unknown function DUF711; COGs: COG2848 conserved hypothetical protein; InterPro IPR007841; KEGG: adg:Adeg_1269 protein of unknown function DUF711; PFAM: protein of unknown function DUF711; SPTR: C9R7V0 Putative uncharacterized protein; PFAM: Uncharacterized ACR (DUF711).
       0.792
Deba_1939
COGs: COG3830 ACT domain-containing protein; InterPro IPR002912; KEGG: mvu:Metvu_1156 ACT domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: C9RHG2 ACT domain-containing protein; PFAM: ACT domain.
       0.792
Deba_1941
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.792
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.739
rnfG
Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
  
 0.730
Deba_1832
ERCC4 domain protein; COGs: COG1948 ERCC4-type nuclease; InterPro IPR006166:IPR011335:IPR020819; KEGG: sfu:Sfum_3788 ERCC4 domain-containing protein; PFAM: ERCC4 domain protein; SMART: ERCC4 domain protein; SPTR: C6MK29 ERCC4 domain protein.
    
 
 0.703
Deba_1477
Conserved hypothetical protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR014729; KEGG: pca:Pcar_2431 hypothetical protein; SPTR: Q3A1T7 Putative uncharacterized protein; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
 
    0.689
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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