STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1945Protein of unknown function DUF2344; COGs: COG1032 Fe-S oxidoreductase; InterProIPR006058:IPR006638:IPR007197:IPR018768:IPR 013785; KEGG: pca:Pcar_2585 Fe-S oxidoreductase; PFAM: Protein of unknown function DUF2344; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q3A1D4 Fe-S oxidoreductase; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); Radical SAM superfamily. (834 aa)    
Predicted Functional Partners:
Deba_1946
Ribonuclease, Rne/Rng family; COGs: COG1530 Ribonuclease G and E; InterPro IPR019307:IPR016027:IPR012340:IPR004659; KEGG: sfu:Sfum_1609 ribonuclease; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; SPTR: A0LIP4 RNAse G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.
       0.834
Deba_1944
RNA-metabolising metallo-beta-lactamase; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: dal:Dalk_2789 RNA-metabolising metallo-beta-lactamase; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: B8FKV9 RNA-metabolising metallo-beta-lactamase; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.
       0.789
Deba_0461
Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR010523:IPR004096:IPR002078:IPR002197:IPR 009057:IPR003593:IPR020441; KEGG: dal:Dalk_3884 sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; 4-vinyl reductase 4VR; Activator of aromatic catabolism; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: B8FCF2 Sigma54 specific transcriptional regulator, Fis family; PFAM: Activator of aromatic catabolism; Bacterial r [...]
  
  
 0.690
Deba_1943
Conserved hypothetical protein; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: dol:Dole_2835 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: A8ZY11 Putative uncharacterized protein; PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1; conserved hypothetical protein, DprA/Smf-related, family 2; Belongs to the LOG family.
       0.529
Deba_0352
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.527
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.521
rsmI
Phosphocarrier, HPr family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.518
Deba_2334
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR011055:IPR019301:IPR016047; KEGG: tte:TTE1975 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; Flagellar protein FlgJ-like; SPTR: Q8R8M0 Membrane proteins related to metalloendopeptidases; PFAM: Rod binding protein; Peptidase family M23.
  
    0.489
Deba_1947
COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006089:IPR006092:IPR006091:IPR006090:IPR 009100:IPR009075:IPR013786:IPR013764; KEGG: dat:HRM2_10010 Acd3; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: C0QL27 Acd3; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
       0.475
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
  
 0.463
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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