STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_19544Fe-4S ferredoxin iron-sulfur binding domain protein; InterPro IPR017900:IPR001450:IPR017896; KEGG: dde:Dde_0043 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q317N2 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain. (73 aa)    
Predicted Functional Partners:
Deba_1953
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR009014:IPR015941; KEGG: gme:Gmet_1307 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Q39W31 Pyruvate flavodoxin/ferredoxin oxidoreductase-like; PFAM: domain.
 
  
 0.957
Deba_1952
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: gur:Gura_2238 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A5G3Q3 Thiamine pyrophosphate enzyme domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
  
 0.954
Deba_1951
COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752:IPR002869; KEGG: drt:Dret_0089 pyruvate/ketoisovalerate oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: C0GP42 Pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase.
 
  
 0.949
Deba_1275
COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR019818; KEGG: dol:Dole_1908 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A8ZSH5 Isocitrate dehydrogenase [NADP]; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
     
  0.900
Deba_2361
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR009014:IPR015941:IPR002880; KEGG: hor:Hore_06780 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: B8CVW6 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), alpha subunit; PFAM: domain.
 
  
 0.822
Deba_0433
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013785; KEGG: cag:Cagg_1303 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: B8G8E9 Pyruvate carboxyltransferase; PFAM: HMGL-like.
   
 
 0.817
Deba_2363
COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR002869:IPR019752; KEGG: hor:Hore_06800 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: B8CVW8 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase.
 
  
 0.817
Deba_2362
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: kol:Kole_2159 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C5CIQ3 Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
  
 0.808
argH
COGs: COG0165 Argininosuccinate lyase; InterProIPR020557:IPR003031:IPR000362:IPR008948:IPR 009049; KEGG: dma:DMR_26520 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C4XUC1 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
    
  0.806
Deba_1152
COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 
 0.803
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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