STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_1961RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (503 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.946
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.933
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.932
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.932
Deba_1960
ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: sat:SYN_00946 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q2LSN4 ABC transporter ATP-binding protein; PFAM: ABC transporter.
  
  
 0.830
Deba_1963
Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178:IPR016152; KEGG: sfu:Sfum_2067 putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: A0LJZ8 Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.822
Deba_1212
Putative sigma54 specific transcriptional regulator; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR003593; KEGG: aav:Aave_0172 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; SMART: AAA ATPase; SPTR: A1TIJ6 Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Sigma-54 interaction domain.
 
   
 0.788
Deba_2179
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR009057:IPR020441:IPR002078:IPR000014:IPR 000700:IPR001610:IPR003593:IPR013656:IPR002197; KEGG: sfu:Sfum_3592 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; PAC repeat-containing protein; SPTR: A0LPB0 Sigma54 specific transcriptional regulator, Fis fam [...]
 
   
 0.784
Deba_0461
Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR010523:IPR004096:IPR002078:IPR002197:IPR 009057:IPR003593:IPR020441; KEGG: dal:Dalk_3884 sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; 4-vinyl reductase 4VR; Activator of aromatic catabolism; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: B8FCF2 Sigma54 specific transcriptional regulator, Fis family; PFAM: Activator of aromatic catabolism; Bacterial r [...]
 
  
 0.783
Deba_0625
Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR003018:IPR003593:IPR002078:IPR009057:IPR 020441:IPR002197; KEGG: sfu:Sfum_1010 NifA subfamily transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; AAA ATPase; SPTR: C0GSN4 Transcriptional regulator, NifA subfamily, Fis Family; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRF [...]
 
   
 0.782
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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