Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]

DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.

Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.

DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.

Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.

COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR005101; KEGG: hoh:Hoch_4973 DNA photolyase FAD-binding protein; PFAM: DNA photolyase FAD-binding; PRIAM: Deoxyribodipyrimidine photo-lyase; SPTR: D0LU98 DNA photolyase FAD-binding protein; PFAM: FAD binding domain of DNA photolyase; TIGRFAM: photolyase PhrII.

parB-like partition protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: gme:Gmet_3412 chromosome segregation DNA-binding protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: B9XGP1 ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.

COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dol:Dole_1974 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A8ZT95 Histone deacetylase superfamily; PFAM: Histone deacetylase domain.