STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Deba_2013Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR001789:IPR003018:IPR003607:IPR006674:IPR 011006; KEGG: sfu:Sfum_3292 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: A0LNG3 Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain [...] (534 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 0.958
Deba_3177
Diguanylate cyclase with PAS/PAC sensor; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR000014:IPR000160:IPR003660:IPR013767:IPR 013655:IPR013656:IPR000700:IPR001610; KEGG: dar:Daro_1156 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein; PA [...]
 
 0.944
Deba_0668
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterProIPR000014:IPR000160:IPR000700:IPR013767:IPR 006089; KEGG: dsa:Desal_3020 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Q2BH87 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) (Fragment); TIGRFAM: diguanylate cyclase; PAS sensor protein; manually curated; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 0.923
Deba_2286
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: amc:MADE_03704 GGDEF domain protein; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; SPTR: A3WMD3 Phytochrome sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 0.871
Deba_0403
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR003661:IPR 003594:IPR011006:IPR009082:IPR000014:IPR001610:IPR004358:I PR005467:IPR000700; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region [...]
 
 
0.866
Deba_0503
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000644:IPR000160; KEGG: drt:Dret_0176 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: C8WZK3 Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.847
Deba_2125
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003594:IPR009082:IPR004358:IPR005467:IPR 000014:IPR000700:IPR003661:IPR013163:IPR013656:IPR013767; KEGG: dat:HRM2_07890 two domain sensory box histidine kinase (methyl-accepting chemotaxis transducer/Ntr-family protein); PFAM: Cache type 2 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain cont [...]
 
 
 0.836
Deba_2616
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR011006:IPR009082:IPR013655:IPR013656:IPR013767:I PR004358:IPR005467:IPR000700; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-contai [...]
 
 
 0.816
Deba_0862
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000700:IPR011006:IPR009082:IPR004358:I PR013767:IPR000169; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: A0LKY0 Sensor p [...]
 
 0.815
Deba_0181
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001638:IPR013656:IPR003661:IPR003594:IPR 005467:IPR000014:IPR000700:IPR009082:IPR001610:IPR004358; KEGG: dsa:Desal_2320 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: extracellular solute-binding protein family 3; PAS fold-4 domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain pr [...]
 
 
 0.813
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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