Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2015Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467; KEGG: tye:THEYE_A0747 sensor histidine kinase, putative; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: B5YK24 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (242 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 
 0.970
Deba_2016
PBS lyase HEAT domain protein repeat-containing protein; COGs: COG1413 FOG: HEAT repeat; InterPro IPR004155:IPR016024:IPR011989; KEGG: dds:Ddes_1378 heat domain containing protein; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SMART: PBS lyase HEAT domain protein repeat-containing protein; SPTR: B8J0K3 HEAT domain containing protein; PFAM: PBS lyase HEAT-like repeat; HEAT repeat.
 
     0.802
Deba_2014
InterPro IPR009875; KEGG: dba:Dbac_0482 type IV pilus assembly PilZ; PFAM: type IV pilus assembly PilZ; SPTR: C0GRU4 Type IV pilus assembly PilZ; PFAM: PilZ domain.
       0.773
Deba_2013
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR001789:IPR003018:IPR003607:IPR006674:IPR 011006; KEGG: sfu:Sfum_3292 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: A0LNG3 Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain [...]
  
 
 0.712
Deba_1160
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR011006:IPR009082:IPR 011620:IPR013655:IPR013656:IPR013767:IPR003661:IPR001789:I PR005467:IPR000014:IPR000700:IPR001610; KEGG: cyn:Cyan7425_3579 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein [...]
 
 
 
 0.702
Deba_0130
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 005467:IPR000014:IPR000700:IPR011006:IPR009082:IPR002226:I PR001610:IPR004358; KEGG: sfu:Sfum_1337 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-contain [...]
 
 
 
 0.700
Deba_0630
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR011006:IPR009082:IPR004358:IPR013656:I PR013767; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; re [...]
 
 
 
 0.676
Deba_0403
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR003661:IPR 003594:IPR011006:IPR009082:IPR000014:IPR001610:IPR004358:I PR005467:IPR000700; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region [...]
 
 
 
 0.670
Deba_2017
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: lip:LI1142 CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q1MP81 CheY-like receiver; PFAM: Response regulator receiver domain.
  
   0.668
Deba_1323
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700:IPR004358:IPR003018:I PR001610:IPR011006:IPR009082; KEGG: dal:Dalk_0107 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; GAF domain protein; PAC repeat-containing protein; response [...]
 
 
 
 0.664
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.