Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Deba_2046Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711:IPR011991; KEGG: dvm:DvMF_1479 transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: B8DLQ1 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain. (237 aa)    
Predicted Functional Partners:
Deba_2045
Protein of unknown function DUF192; COGs: COG1430 conserved hypothetical protein; InterPro IPR003795; KEGG: rce:RC1_1079 hypothetical protein; PFAM: protein of unknown function DUF192; SPTR: B4VP74 Uncharacterized ACR, COG1430, putative; PFAM: Uncharacterized ACR, COG1430.
 
     0.798
Deba_0773
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: dal:Dalk_2985 transcriptional regulator, IclR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: B8FL40 Transcriptional regulator, IclR family; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
  
  
 0.706
Deba_0337
COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit.
  
    0.692
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
 
   
 0.575
Deba_1504
Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR008920:IPR011711:IPR011991; KEGG: bbe:BBR47_15820 probable transcriptional regulator; PFAM: regulatory protein GntR HTH; fatty acid responsive transcription factor FadR domain protein; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: C0Z989 Probable transcriptional regulator; PFAM: FadR C-terminal domain; Bacterial regulatory proteins, gntR family; TIGRFAM: fatty acid metabolism transcriptional regulator FadR.
 
  
 0.534
Deba_2047
Conserved hypothetical protein; InterPro IPR016024:IPR011989; KEGG: dal:Dalk_2376 hypothetical protein; SPTR: Q1NTE0 HEAT.
       0.522
Deba_2048
Flavodoxin/nitric oxide synthase; COGs: COG0426 flavoprotein; InterPro IPR008254:IPR016440; KEGG: sfu:Sfum_3253 flavodoxin/nitric oxide synthase; PFAM: flavodoxin/nitric oxide synthase; SPTR: C8R2S6 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin.
       0.522
Deba_1647
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: dal:Dalk_4913 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: B8FDF8 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
 
   
 0.500
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
       0.497
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.492
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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