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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (234 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.995
Deba_0423
COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dol:Dole_1493 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: A8ZZE4 Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
 
  
 0.952
Deba_2055
KEGG: azc:AZC_0448 hypothetical protein; SPTR: A6C2E0 Putative uncharacterized protein.
       0.576
queA
S-adenosylmethionine/tRNA-ribosyltransferase-iso merase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
   
 0.566
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
 
   
 0.507
fur-2
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: drt:Dret_0141 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: C8R2S3 Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
     
 0.488
Deba_2012
InterPro IPR005186; KEGG: nis:NIS_0641 flagellar protein FlaG; PFAM: flagellar protein FlaG protein; SPTR: Q9ZFD5 FlaG (Fragment); PFAM: FlaG protein.
    
   0.465
Deba_0985
COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR009051:IPR017900:IPR012285:IPR017896; KEGG: drm:Dred_0633 putative heterodisulfide reductase, C subunit; SPTR: A7BT24 Heterodisulfide reductase subunit C.
   
    0.460
Deba_1136
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR006662:IPR012336:IPR013766:IPR017937:IPR 012335:IPR017936:IPR005746; KEGG: sfu:Sfum_1708 thioredoxin; PFAM: Thioredoxin domain; SPTR: A0LIZ3 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
  
 0.458
Deba_2052
KEGG: csc:Csac_0688 hypothetical protein; SPTR: C8S5Y8 Putative uncharacterized protein.
     
 0.431
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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