STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2068KEGG: dsa:Desal_1340 hypothetical protein; SPTR: C6C206 Putative uncharacterized protein; manually curated. (465 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.777
Deba_0183
OmpA/MotB domain protein; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665:IPR006690:IPR006664; KEGG: nha:Nham_0236 OmpA/MotB; PFAM: OmpA/MotB domain protein; SPTR: Q1QRL1 OmpA/MotB; PFAM: OmpA family.
  
 
 0.543
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.543
Deba_2069
COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504:IPR012677; KEGG: dma:DMR_11610 RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: C4XLR4 RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain).
       0.525
Deba_0596
Lytic transglycosylase catalytic; InterPro IPR008258:IPR018392:IPR002482; KEGG: pca:Pcar_2042 membrane-bound lytic murein transglycosylase D precursor; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Q3A2X4 Membrane-bound lytic murein transglycosylase D; PFAM: Transglycosylase SLT domain; LysM domain.
   
 
 0.521
Deba_2435
Lytic transglycosylase catalytic; InterPro IPR002482:IPR008258:IPR018392; KEGG: sfu:Sfum_0750 peptidoglycan-binding LysM; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: A0LG96 Peptidoglycan-binding LysM; PFAM: Transglycosylase SLT domain; LysM domain.
   
 
 0.521
Deba_0415
Peptidoglycan-binding lysin domain protein; InterPro IPR018392:IPR002482; KEGG: mpt:Mpe_A2160 putative transmembrane protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: A2SHS7 Putative transmembrane protein; PFAM: LysM domain.
   
 
 0.518
Deba_0671
Peptidoglycan-binding lysin domain protein; InterPro IPR002482:IPR018392; KEGG: rmr:Rmar_0215 lytic transglycosylase catalytic; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: D0MD11 Lytic transglycosylase catalytic; PFAM: LysM domain.
   
 
 0.518
Deba_2410
Peptidoglycan-binding lysin domain protein; InterPro IPR002482:IPR018392; KEGG: rmr:Rmar_0215 lytic transglycosylase catalytic; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: A3HWY5 Putative membrane-bound lytic murein transglycosylase; PFAM: LysM domain.
   
 
 0.518
Deba_3097
Tetratricopeptide TPR_2 repeat protein; InterProIPR001440:IPR013105:IPR019734:IPR013026:IPR 011990; KEGG: dat:HRM2_20780 tetratricopeptide (TPR) domain protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SPTR: C0QDB3 Tetratricopeptide (TPR) domain protein; PFAM: ChAPs (Chs5p-Arf1p-binding proteins); TIGRFAM: putative PEP-CTERM system TPR-repeat lipoprotein.
  
  
 0.518
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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