STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2077Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: dma:DMR_32850 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: C4XJM9 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. (95 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.955
Deba_2078
Domain of unknown function DUF1732; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: gem:GM21_1049 YicC domain protein; PFAM: domain of unknown function DUF1732; YicC domain protein; SPTR: C6E2G4 YicC domain protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255.
 
    0.936
Deba_2075
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: afw:Anae109_2230 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: A7HCI6 RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase [...]
       0.795
Deba_2079
KEGG: dol:Dole_1913 GTP-binding protein; SPTR: A8ZSI0 Conserved hypothetical GTP-binding protein.
       0.790
Deba_2080
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterProIPR001732:IPR014026:IPR014027:IPR016040:IPR 008927:IPR013328:IPR017476; KEGG: tye:THEYE_A0998 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: B5YKR5 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domai [...]
       0.656
Deba_2089
Protein of unknown function DUF343; InterPro IPR005651; KEGG: dol:Dole_1914 hypothetical protein; PFAM: protein of unknown function DUF343; SPTR: A8ZSI1 Putative uncharacterized protein; Belongs to the UPF0434 family.
       0.577
Deba_2082
rfaE bifunctional protein; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611:IPR011913; KEGG: sfu:Sfum_3634 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: A0LPF2 PfkB domain protein; TIGRFAM: rfaE bifunctional protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I.
       0.575
Deba_2095
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
       0.564
Deba_2096
Polysaccharide deacetylase; InterPro IPR002509:IPR011330; KEGG: gme:Gmet_0882 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Q39XA0 Polysaccharide deacetylase; PFAM: Polysaccharide deacetylase.
     
 0.550
Deba_2081
O-antigen polymerase; InterPro IPR018271:IPR007016; KEGG: tye:THEYE_A0427 O-antigen polymerase family; PFAM: O-antigen polymerase; SPTR: B5YJ59 O-Antigen Polymerase family; PFAM: O-Antigen ligase.
       0.531
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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