Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (373 aa)    
Predicted Functional Partners:
Deba_2095
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 0.999
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.993
Deba_3129
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 0.988
Deba_2093
COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: sfu:Sfum_0376 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: A0LF74 Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase.
 
  
 0.968
lpxA
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.940
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.938
Deba_2090
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011908; KEGG: tye:THEYE_A0945 lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; SPTR: A1HRG7 Lipopolysaccharide heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase II.
 
  
 0.911
Deba_3124
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR004800:IPR001347:IPR000644; KEGG: dol:Dole_2110 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: A8ZTY1 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.901
Deba_2104
Protein of unknown function DUF1009; COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: dat:HRM2_22450 hypothetical protein; PFAM: protein of unknown function DUF1009; SPTR: C0QEK1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1009).
 
   
 0.891
Deba_2092
Lipopolysaccharide heptosyltransferase II; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011910; KEGG: gsu:GSU2256 ADP-heptose--LPS heptosyltransferase II, putative; PFAM: glycosyl transferase family 9; SPTR: Q74AU4 ADP-heptose--LPS heptosyltransferase II, putative; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
 
  
 0.888
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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