STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_2095Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (430 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.999
Deba_2090
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011908; KEGG: tye:THEYE_A0945 lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; SPTR: A1HRG7 Lipopolysaccharide heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase II.
  
 0.994
Deba_2093
COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: sfu:Sfum_0376 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: A0LF74 Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase.
 
  
 0.994
Deba_2088
Lipopolysaccharide heptosyltransferase III; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011916; KEGG: sfu:Sfum_0370 lipopolysaccharide heptosyltransferase III, putative; PFAM: glycosyl transferase family 9; SPTR: B9YYN7 Lipopolysaccharide heptosyltransferase III; TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase III, putative.
  
 0.985
Deba_2092
Lipopolysaccharide heptosyltransferase II; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011910; KEGG: gsu:GSU2256 ADP-heptose--LPS heptosyltransferase II, putative; PFAM: glycosyl transferase family 9; SPTR: Q74AU4 ADP-heptose--LPS heptosyltransferase II, putative; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
 
  
 0.985
Deba_2087
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dar:Daro_0153 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: B9YYN8 Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1.
    
 0.978
kdsB
3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.960
Deba_2096
Polysaccharide deacetylase; InterPro IPR002509:IPR011330; KEGG: gme:Gmet_0882 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Q39XA0 Polysaccharide deacetylase; PFAM: Polysaccharide deacetylase.
    
  0.955
Deba_3129
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
  
 
0.919
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.910
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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