STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2095Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (430 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.999
Deba_2090
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011908; KEGG: tye:THEYE_A0945 lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; SPTR: A1HRG7 Lipopolysaccharide heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase II.
  
 0.994
Deba_2093
COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: sfu:Sfum_0376 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: A0LF74 Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase.
 
  
 0.994
Deba_2088
Lipopolysaccharide heptosyltransferase III; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011916; KEGG: sfu:Sfum_0370 lipopolysaccharide heptosyltransferase III, putative; PFAM: glycosyl transferase family 9; SPTR: B9YYN7 Lipopolysaccharide heptosyltransferase III; TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase III, putative.
  
 0.985
Deba_2092
Lipopolysaccharide heptosyltransferase II; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011910; KEGG: gsu:GSU2256 ADP-heptose--LPS heptosyltransferase II, putative; PFAM: glycosyl transferase family 9; SPTR: Q74AU4 ADP-heptose--LPS heptosyltransferase II, putative; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II.
 
  
 0.985
Deba_2083
COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: tye:THEYE_A0426 glycosyl transferase, family 9; PFAM: glycosyl transferase family 9; SPTR: B5YJ58 Glycosyl transferase, family 9; PFAM: Glycosyltransferase family 9 (heptosyltransferase).
  
 0.984
Deba_2081
O-antigen polymerase; InterPro IPR018271:IPR007016; KEGG: tye:THEYE_A0427 O-antigen polymerase family; PFAM: O-antigen polymerase; SPTR: B5YJ59 O-Antigen Polymerase family; PFAM: O-Antigen ligase.
    
 0.983
kdsB
3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.980
Deba_2087
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dar:Daro_0153 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: B9YYN8 Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1.
    
 0.979
Deba_2098
Glycosyl transferase family 39; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: gme:Gmet_0887 glycosyl transferase family protein; PFAM: glycosyl transferase family 39; SPTR: Q39X95 Glycosyl transferase, family 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
 
  
 0.970
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.