STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2101Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (597 aa)    
Predicted Functional Partners:
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.852
Deba_2104
Protein of unknown function DUF1009; COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: dat:HRM2_22450 hypothetical protein; PFAM: protein of unknown function DUF1009; SPTR: C0QEK1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1009).
 
     0.852
lpxA
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.852
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
  
 0.831
Deba_2103
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104:IPR016040; KEGG: aeh:Mlg_0316 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Q0ABW6 Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
  
 0.800
Deba_2100
Phosphoesterase PA-phosphatase related protein; InterPro IPR000326:IPR016118; KEGG: tye:THEYE_A1814 lipid A 1-phosphatase; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: B5K7V0 PAP2 superfamily protein; PFAM: PAP2 superfamily.
     
 0.787
Deba_2098
Glycosyl transferase family 39; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: gme:Gmet_0887 glycosyl transferase family protein; PFAM: glycosyl transferase family 39; SPTR: Q39X95 Glycosyl transferase, family 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
     
 0.786
Deba_2099
Glycosyl transferase family 39; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: tgr:Tgr7_3093 glycosyl transferase family 39; PFAM: glycosyl transferase family 39; SPTR: B8GQ15 Glycosyl transferase family 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
     
 0.786
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
  
 0.770
bamA
Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
 
   0.740
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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