STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
lolDABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (229 aa)    
Predicted Functional Partners:
Deba_2111
Lipoprotein releasing system, transmembrane protein, LolC/E family; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838:IPR011925; KEGG: sfu:Sfum_3743 LolC/E family lipoprotein releasing system, transmembrane protein; PFAM: protein of unknown function DUF214; SPTR: A0LPR1 Lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family.
 
 0.993
Deba_1643
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: protein of unknown function DUF214; SPTR: A0LM36 Macrolide export ATP-binding/permease protein macB; PFAM: Predicted permease.
 
 0.989
Deba_1117
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.859
bamA
Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
     
 0.780
Deba_1806
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dat:HRM2_00690 ABC-type transporter, predicted premease protein; PFAM: protein of unknown function DUF214; SPTR: Q1JW27 Putative uncharacterized protein; manually curated; PFAM: Predicted permease.
  
 
 0.761
Deba_1466
KEGG: dat:HRM2_08300 ABC-type transporter, permease protein; SPTR: C0QJU0 ABC-type transporter, permease protein.
  
 
 0.750
Deba_1467
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dat:HRM2_08300 ABC-type transporter, permease protein; PFAM: protein of unknown function DUF214; SPTR: C0QJU0 ABC-type transporter, permease protein; PFAM: Predicted permease.
  
 
 0.750
lysS
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR018149:IPR004365:IPR004364:IPR016027:IPR 006195:IPR012340:IPR002313; KEGG: drt:Dret_2234 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: C8X521 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
     0.711
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
   
 
 0.669
Deba_2108
InterPro IPR005632; KEGG: drt:Dret_2230 outer membrane chaperone Skp (OmpH); PFAM: outer membrane chaperone Skp (OmpH); SPTR: C8X517 Outer membrane chaperone Skp (OmpH); PFAM: Outer membrane protein (OmpH-like).
     
 0.662
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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