Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_2149COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_3267 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: B8FJ30 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (290 aa)    
Predicted Functional Partners:
Deba_2152
KEGG: dal:Dalk_3264 hypothetical protein; SPTR: B8FJ27 Putative uncharacterized protein; PFAM: Methylene-tetrahydrofolate reductase C terminal.
 
  
 0.913
Deba_0238
Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489:IPR011005; KEGG: dol:Dole_3182 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: A9A066 Dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme.
 
  
 0.816
Deba_2225
KEGG: dat:HRM2_30870 putative zinc-finger protein; SPTR: C0QKT0 Putative zinc-finger protein; PFAM: Methylene-tetrahydrofolate reductase C terminal.
 
  
 0.799
Deba_1009
Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4619 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: B8FNL6 Dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme.
 
  
 0.792
Deba_2205
KEGG: deb:DehaBAV1_0492 hypothetical protein; SPTR: A5FRU6 Putative uncharacterized protein; PFAM: Cobalamin-independent synthase, Catalytic domain.
  
  
 0.792
Deba_1649
Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4910 methionine synthase; PFAM: dihydropteroate synthase DHPS; SPTR: B8FDF5 Methionine synthase; PFAM: Pterin binding enzyme.
 
  
 0.735
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.684
Deba_0872
KEGG: dal:Dalk_2588 hypothetical protein; SPTR: B8FIP0 Putative uncharacterized protein.
  
  
 0.677
Deba_2151
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: mta:Moth_1193 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Q2RJ82 Methyl-viologen-reducing hydrogenase, delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
     
 0.673
Deba_2153
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_2779 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: B8FKU9 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
    
0.656
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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