Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2156Hypothetical protein; KEGG: mex:Mext_1994 beta-lactamase domain-containing protein; SPTR: A9W487 Beta-lactamase domain protein. (161 aa)    
Predicted Functional Partners:
Deba_1382
COGs: COG0460 Homoserine dehydrogenase; InterProIPR005106:IPR001342:IPR002912:IPR019811:IPR 016204:IPR016040; KEGG: gsu:GSU1693 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Q74CI0 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
  
 
 0.844
Deba_2157
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003594:IPR009082:IPR004358:IPR005467:IPR 000014:IPR000700:IPR001610:IPR003661:IPR013656:IPR013767; KEGG: sfu:Sfum_2807 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: A0LM33 Sensor protein; TI [...]
       0.813
Deba_2158
COGs: COG5002 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR004358:IPR 005467:IPR001789:IPR000014:IPR003661:IPR013656; KEGG: dal:Dalk_2419 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; SPTR: B8FB26 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator rec [...]
  
    0.794
Deba_1359
COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: dal:Dalk_4397 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: B8FNA7 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
  
 
 0.775
Deba_2155
Hypothetical protein; KEGG: ach:Achl_0449 alpha/beta hydrolase fold-3 domain protein; SPTR: B8HAI7 Alpha/beta hydrolase fold-3 domain protein.
       0.773
Deba_2154
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR011006:IPR001789; KEGG: dal:Dalk_3262 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FJ25 Response regulator receiver protein; PFAM: Response regulator receiver domain.
     
 0.743
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.734
Deba_2153
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_2779 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: B8FKU9 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.730
Deba_0002
COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR000774:IPR001179:IPR008104; KEGG: pca:Pcar_0774 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; SPTR: Q3A6H4 Peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Domain amino terminal to FKBP-type peptidyl-prolyl isomerase.
    
   0.727
Deba_2149
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_3267 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: B8FJ30 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.654
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (16%) [HD]