STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2180Transcriptional regulator, TetR family; InterProIPR009057:IPR011075:IPR001647:IPR012287:IPR 015292; KEGG: mca:MCA1598 TetR family transcriptional regulator; PFAM: regulatory protein TetR; Transcriptional regulator TetR; SPTR: Q607Z9 Transcriptional regulator, TetR family; PFAM: Domain of unknown function (DUF1956); Bacterial regulatory proteins, tetR family. (216 aa)    
Predicted Functional Partners:
Deba_2182
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dal:Dalk_1444 efflux transporter, RND family, MFP subunit; SPTR: B8FA48 Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   
 0.861
Deba_2183
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR000209; KEGG: dal:Dalk_1445 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: B8FA49 Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.850
Deba_2181
COGs: COG1538 Outer membrane protein; InterPro IPR003423:IPR010131; KEGG: dal:Dalk_1443 RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; SPTR: B8FA47 RND efflux system, outer membrane lipoprotein, NodT family; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.
     
 0.800
Deba_2179
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR009057:IPR020441:IPR002078:IPR000014:IPR 000700:IPR001610:IPR003593:IPR013656:IPR002197; KEGG: sfu:Sfum_3592 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; PAC repeat-containing protein; SPTR: A0LPB0 Sigma54 specific transcriptional regulator, Fis fam [...]
       0.515
ftsH-2
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
    0.472
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
   
 
 0.435
Deba_1076
parB-like partition protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: gme:Gmet_3412 chromosome segregation DNA-binding protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: B9XGP1 ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
  
 
 
 0.411
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.408
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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