STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2196Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dma:DMR_02310 amidohydrolase family protein; PFAM: amidohydrolase; SPTR: C4XGE2 Amidohydrolase family protein; PFAM: Amidohydrolase family. (402 aa)    
Predicted Functional Partners:
mqnE
Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
  
  0.988
Deba_2375
Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase.
    
 0.910
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
     0.890
mqnD
Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
  
     0.524
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
   
 
 0.492
Deba_2193
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR011990:IPR001173; KEGG: ade:Adeh_1337 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Q2IQM7 Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2.
       0.482
Deba_2710
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303:IPR014710:IPR011051:IPR013096; KEGG: chl:Chy400_0637 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; Cupin 2 conserved barrel domain protein; SPTR: B9LJP0 Class II aldolase/adducin family protein; PFAM: Cupin domain; Class II Aldolase and Adducin N-terminal domain.
 
   
 0.454
Deba_1158
COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: sfu:Sfum_0288 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; SPTR: A0LEY7 4-hydroxybenzoate polyprenyltransferase, putative; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family.
 
   
 0.451
Deba_2488
COGs: COG2367 Beta-lactamase class A; InterPro IPR000871:IPR012338:IPR001466:IPR017909; KEGG: bcn:Bcen_3438 beta-lactamase; PFAM: beta-lactamase; PRIAM: Beta-lactamase; SPTR: C0LP01 Beta-lactamase LUT-5; PFAM: Beta-lactamase.
  
    0.435
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
     0.433
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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