STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2213HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005833:IPR005834:IPR006439; KEGG: dal:Dalk_3700 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8FLN4 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif [...] (214 aa)    
Predicted Functional Partners:
Deba_1536
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166:IPR016164:IPR006094:IPR004113:IPR 016167:IPR016168:IPR000542; KEGG: dat:HRM2_18570 GlcD2; PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: C0QBU7 GlcD2; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
 
  
 0.929
Deba_1537
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR009051:IPR004017:IPR012285:IPR017896:IPR 017900; KEGG: gem:GM21_0576 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C6DZR8 Putative uncharacterized protein; PFAM: Cysteine-rich domain.
 
  
 0.918
Deba_0702
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: dvm:DvMF_0135 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8DNN9 Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfami [...]
     
  0.900
Deba_2214
KEGG: dal:Dalk_1271 hypothetical protein; SPTR: B8F9M8 Putative uncharacterized protein.
       0.561
Deba_2215
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: drt:Dret_0273 molybdopterin oxidoreductase, transmembrane subunit, putative; PFAM: Polysulphide reductase NrfD; SPTR: C8WZV0 Molybdopterin oxidoreductase, transmembrane subunit; PFAM: Polysulphide reductase, NrfD.
       0.550
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.529
Deba_2306
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
    
   0.513
Deba_0438
Dinitrogenase iron-molybdenum cofactor biosynthesis protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR003731; KEGG: dsa:Desal_0442 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein; SPTR: C6BX29 Dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Radical SAM superfamily; Dinitrogenase iron-molybdenum cofactor.
  
    0.508
Deba_2210
Radical SAM domain protein; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197; KEGG: sfu:Sfum_1766 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: A0LJ51 Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
    0.508
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.508
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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