STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2236Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR011010:IPR010998:IPR013762:IPR002104; KEGG: adg:Adeg_0419 integrase family protein; PFAM: integrase family protein; SPTR: A8UWI5 Phage integrase; PFAM: Phage integrase family; Belongs to the 'phage' integrase family. (397 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.631
Deba_1274
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: ajs:Ajs_3540 ComF family protein; PFAM: phosphoribosyltransferase; SPTR: A1WBM8 ComF family protein; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
   
    0.602
Deba_0478
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099:IPR016040; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: B8FFQ7 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
  
    0.540
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.480
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.443
Deba_2539
KEGG: cch:Cag_1524 DNA-damage-inducible protein D; SPTR: Q3AQE6 DNA-damage-inducible protein D.
 
  
 0.420
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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