Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_2236Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR011010:IPR010998:IPR013762:IPR002104; KEGG: adg:Adeg_0419 integrase family protein; PFAM: integrase family protein; SPTR: A8UWI5 Phage integrase; PFAM: Phage integrase family; Belongs to the 'phage' integrase family. (397 aa)    
Predicted Functional Partners:
Deba_1274
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: ajs:Ajs_3540 ComF family protein; PFAM: phosphoribosyltransferase; SPTR: A1WBM8 ComF family protein; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
   
    0.617
Deba_0478
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099:IPR016040; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: B8FFQ7 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
  
    0.587
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.573
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.525
rpsU
Ribosomal protein S21; InterPro IPR018278:IPR001911; KEGG: pca:Pcar_2255 30S ribosomal protein S21; SPTR: Q1JW03 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; manually curated; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
   
 
 0.509
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
 
 0.482
rpsI
COGs: COG0103 Ribosomal protein S9; InterProIPR014721:IPR020568:IPR000754:IPR017441:IPR 020574; KEGG: pca:Pcar_1899 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: Q3A3B7 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.475
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
    
 
 0.474
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
 
 0.474
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
    
 
 0.471
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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