Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Deba_2241Bifunctional DNA primase/polymerase; InterPro IPR015330; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal. (626 aa)    
Predicted Functional Partners:
Deba_2240
HNH endonuclease; InterPro IPR003615:IPR002711; KEGG: dvu:DVU1505 holin, putative; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: C5RJY1 HNH endonuclease; manually curated; PFAM: HNH endonuclease.
  
  
 0.810
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.800
Deba_1727
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 
 0.780
Deba_2239
Terminase; COGs: COG4626 Phage terminase-like protein large subunit; InterPro IPR005021; KEGG: pap:PSPA7_5155 phage terminase, large subunit, putative; PFAM: Terminase; SPTR: A6VBQ6 Phage terminase, large subunit, putative; PFAM: Phage Terminase.
     
 0.780
Deba_2242
Hypothetical protein.
       0.773
Deba_2185
UvrD/REP helicase; COGs: COG1379 conserved hypothetical protein; InterPro IPR014016:IPR014017:IPR000212; KEGG: rmr:Rmar_0317 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0MDM9 UvrD/REP helicase; PFAM: UvrD/REP helicase; TIGRFAM: conserved hypothetical protein TIGR00375.
  
  
 0.739
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.739
Deba_2238
InterPro IPR006433:IPR006444; KEGG: cth:Cthe_2866 phage major capsid protein, HK97; PFAM: peptidase U35 phage prohead HK97; major capsid protein HK97; SPTR: B4BHH3 Major capsid protein HK97; TIGRFAM: phage major capsid protein, HK97 family; PFAM: Phage capsid family; Caudovirus prohead protease; TIGRFAM: phage major capsid protein, HK97 family; phage prohead protease, HK97 family.
 
   
 0.738
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.725
Deba_0816
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: dma:DMR_07030 ATP-dependent DNA helicase; PFAM: UvrD/REP helicase; SPTR: Q1NUA0 UvrD/REP helicase; PFAM: UvrD/REP helicase.
  
  
 0.696
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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