STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2264COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR013785:IPR004136; KEGG: dol:Dole_1182 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase NPD; SPTR: A8ZXN0 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase. (321 aa)    
Predicted Functional Partners:
Deba_3133
Short-chain dehydrogenase/reductase SDR; COGs: COG3425 3-hydroxy-3-methylglutaryl CoA synthase; InterProIPR016040:IPR016039:IPR016083:IPR013747:IPR 002878:IPR002198:IPR003033:IPR002347; KEGG: dol:Dole_1550 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; protein of unknown function DUF35; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Sterol-binding domain protein; SPTR: A8ZZV4 Short-chain dehydrogenase/reductase SDR; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C term [...]
  
  
 0.835
Deba_2263
KEGG: hypothetical protein; SPTR: A9SND1 Predicted protein.
       0.686
Deba_2386
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
  
 0.658
Deba_2144
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
 
  
 0.635
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.627
Deba_1955
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterProIPR014043:IPR016035:IPR016036:IPR001227:IPR 004410; KEGG: dal:Dalk_3440 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: B8FLI2 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
  
 0.618
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
    
 0.543
Deba_2265
COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR016196:IPR003594:IPR011701; KEGG: bbe:BBR47_11350 hypothetical protein; PFAM: major facilitator superfamily MFS_1; ATP-binding region ATPase domain protein; SPTR: C0Z6F5 Conserved hypothetical membrane protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Major Facilitator Superfamily.
  
  
 0.530
Deba_2489
InterPro IPR002539; KEGG: dal:Dalk_5057 MaoC domain protein dehydratase; PFAM: MaoC domain protein dehydratase; SPTR: B8FDU7 MaoC domain protein dehydratase; PFAM: MaoC like domain.
  
    0.512
Deba_3134
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterProIPR016040:IPR016083:IPR002539:IPR002198:IPR 003033:IPR002347; KEGG: dal:Dalk_3192 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; MaoC domain protein dehydratase; Sterol-binding domain protein; SPTR: B8FGH3 Short-chain dehydrogenase/reductase SDR; PFAM: MaoC like domain; short chain dehydrogenase; SCP-2 sterol transfer family.
  
  
 0.507
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.