STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2297KEGG: pca:Pcar_0849 hypothetical protein; SPTR: Q3A6A2 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3450). (258 aa)    
Predicted Functional Partners:
Deba_2296
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR017270:IPR002898; KEGG: pca:Pcar_0848 TolR-like transport protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Q3A6A3 TolR-like transport protein; PFAM: Protein of unknown function (DUF3450); MotA/TolQ/ExbB proton channel family.
 
  
 0.955
Deba_2294
COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: dal:Dalk_3527 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: B8FC10 Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR.
 
   
 0.951
Deba_2293
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
  
 0.947
Deba_2292
TPR repeat-containing protein; InterPro IPR011990:IPR019734:IPR013026:IPR001440; KEGG: pca:Pcar_0844 hypothetical protein; PFAM: TPR repeat-containing protein; SPTR: Q3A6A7 Putative uncharacterized protein.
 
   
 0.935
Deba_2295
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: pca:Pcar_0847 biopolymer transport protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Q3A6A4 Biopolymer transport protein; PFAM: MotA/TolQ/ExbB proton channel family.
 
  
 0.935
Deba_1207
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.798
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.690
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.667
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.585
Deba_2182
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dal:Dalk_1444 efflux transporter, RND family, MFP subunit; SPTR: B8FA48 Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.574
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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