STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2363COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR002869:IPR019752; KEGG: hor:Hore_06800 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: B8CVW8 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase. (185 aa)    
Predicted Functional Partners:
Deba_2362
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: kol:Kole_2159 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C5CIQ3 Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
 0.997
Deba_1952
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: gur:Gura_2238 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A5G3Q3 Thiamine pyrophosphate enzyme domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
 0.993
Deba_2360
InterPro IPR017896:IPR017900:IPR001450; KEGG: fno:Fnod_0110 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q1K0E9 4Fe-4S ferredoxin, iron-sulfur binding.
 
 
 0.976
Deba_2361
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR009014:IPR015941:IPR002880; KEGG: hor:Hore_06780 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: B8CVW6 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), alpha subunit; PFAM: domain.
 
 
 0.974
Deba_1953
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR009014:IPR015941; KEGG: gme:Gmet_1307 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Q39W31 Pyruvate flavodoxin/ferredoxin oxidoreductase-like; PFAM: domain.
 
 
 0.916
Deba_1275
COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR019818; KEGG: dol:Dole_1908 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A8ZSH5 Isocitrate dehydrogenase [NADP]; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
     
 0.908
Deba_2850
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_1167 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: A0LHF8 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
 
 0.831
Deba_0433
Pyruvate carboxyltransferase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013785; KEGG: cag:Cagg_1303 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: B8G8E9 Pyruvate carboxyltransferase; PFAM: HMGL-like.
    
 0.817
Deba_1954
4Fe-4S ferredoxin iron-sulfur binding domain protein; InterPro IPR017900:IPR001450:IPR017896; KEGG: dde:Dde_0043 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q317N2 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain.
 
  
 0.817
Deba_2364
COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: pth:PTH_2653 ACT domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: A5CYV2 ACT domain-containing protein; PFAM: ACT domain.
  
    0.808
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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