STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2375Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. (229 aa)    
Predicted Functional Partners:
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
    
 0.916
Deba_2196
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dma:DMR_02310 amidohydrolase family protein; PFAM: amidohydrolase; SPTR: C4XGE2 Amidohydrolase family protein; PFAM: Amidohydrolase family.
    
 0.910
mqnD
Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
   
 0.876
Deba_2376
Transcriptional regulator, TetR family; InterPro IPR009057:IPR011075:IPR001647:IPR012287; KEGG: sfu:Sfum_3090 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: A0LMW1 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
   
   0.810
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.808
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
       0.785
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.769
Deba_2380
GCN5-related N-acetyltransferase; InterPro IPR016181:IPR000182; KEGG: dda:Dd703_2189 transcriptional regulator, MarR family with acetyltransferase activity; PFAM: GCN5-related N-acetyltransferase; SPTR: C6C7N4 Transcriptional regulator, MarR family with acetyltransferase activity; PFAM: Acetyltransferase (GNAT) family.
       0.628
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.621
Deba_2381
COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR017938:IPR001783; KEGG: glo:Glov_1750 riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: B3EB72 Riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
  
    0.613
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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