| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Deba_2375 | Deba_2382 | Deba_2375 | Deba_2382 | Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.464 |
| Deba_2375 | nusB | Deba_2375 | Deba_2377 | Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.798 |
| Deba_2375 | ribBA | Deba_2375 | Deba_2379 | Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.759 |
| Deba_2375 | ribH | Deba_2375 | Deba_2378 | Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.790 |
| Deba_2382 | Deba_2375 | Deba_2382 | Deba_2375 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. | 0.464 |
| Deba_2382 | nusB | Deba_2382 | Deba_2377 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.826 |
| Deba_2382 | ribBA | Deba_2382 | Deba_2379 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| Deba_2382 | ribH | Deba_2382 | Deba_2378 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.995 |
| Deba_2382 | rpoZ | Deba_2382 | Deba_0459 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.464 |
| nusA | nusB | Deba_0889 | Deba_2377 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.916 |
| nusA | nusG | Deba_0889 | Deba_2950 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. | 0.977 |
| nusA | rpoA | Deba_0889 | Deba_2911 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.987 |
| nusA | rpoB | Deba_0889 | Deba_2945 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.983 |
| nusA | rpoZ | Deba_0889 | Deba_0459 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.896 |
| nusA | rpsJ | Deba_0889 | Deba_2939 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.973 |
| nusB | Deba_2375 | Deba_2377 | Deba_2375 | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR019963; KEGG: gme:Gmet_3381 purine phosphorylase family protein 1; PFAM: purine or other phosphorylase family 1; SPTR: Q39Q81 Purine and other phosphorylases, family 1; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase. | 0.798 |
| nusB | Deba_2382 | Deba_2377 | Deba_2382 | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.826 |
| nusB | nusA | Deba_2377 | Deba_0889 | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.916 |
| nusB | nusG | Deba_2377 | Deba_2950 | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. | 0.864 |
| nusB | ribBA | Deba_2377 | Deba_2379 | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.908 |