STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2397HflK protein; HflC and HflK could encode or regulate a protease. (348 aa)    
Predicted Functional Partners:
Deba_2398
HflC protein; HflC and HflK could regulate a protease.
 
 
 0.998
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.927
ftsH-2
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.927
hflX
GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
  
  
 0.859
yidC
Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.794
Deba_0427
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterProIPR011765:IPR007863:IPR011249:IPR011237:IPR 001431; KEGG: mxa:MXAN_1141 M16 family peptidase; PFAM: peptidase M16 domain protein; SPTR: Q1DD72 Peptidase, M16 (Pitrilysin) family; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
  
 0.659
Deba_0898
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterProIPR011237:IPR011249:IPR011765:IPR007863:IPR 001431; KEGG: gem:GM21_2975 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: C6E2P4 Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
  
 0.659
Deba_2396
InterPro IPR016196:IPR011701; KEGG: dal:Dalk_5205 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: B8FE94 Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; TIGRFAM: AmpG-related permease.
 
   
 0.604
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
  
 0.560
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 
 0.524
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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