STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
Deba_2479Protein of unknown function DUF534; COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851:IPR007487; KEGG: sfu:Sfum_1505 hypothetical protein; PFAM: protein of unknown function DUF534; inner-membrane translocator; SPTR: A0LIE2 Putative uncharacterized protein; PFAM: ABC transporter substrate binding protein; Branched-chain amino acid transport system / permease component. (946 aa)    
Predicted Functional Partners:
Deba_2478
ABC transporter related protein; COGs: COG1101 ABC-type uncharacterized transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: sfu:Sfum_1504 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: A0LIE1 ABC transporter related; PFAM: ABC transporter.
 
    0.994
Deba_2480
Anti-sigma-factor antagonist; InterPro IPR003658:IPR002645; KEGG: sfu:Sfum_1506 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: A0LIE3 Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
    0.940
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.553
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
     0.499
Deba_1612
Putative PAS/PAC sensor protein; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterProIPR000014:IPR001932:IPR013656:IPR010822:IPR 000700; KEGG: gme:Gmet_2818 putative PAS/PAC sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein; PAS domain containing protein; SPTR: C8QVW1 Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation protein E (SpoIIE); PAS fold; TIGRFAM: PAS domain S-box.
  
    0.459
Deba_2382
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.453
Deba_2424
PhoH family protein; COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR006596:IPR003714; KEGG: dal:Dalk_3397 PhoH family protein; PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; SPTR: B8FLD9 PhoH family protein; PFAM: PhoH-like protein.
   
    0.443
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
       0.442
Deba_1226
COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR010822:IPR001932:IPR011006; KEGG: hmo:HM1_2362 response regulator receiver modulated serine phosphatase; PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; SPTR: B0TIH1 Response regulator receiver modulated serine phosphatase; PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE).
  
    0.428
Deba_1390
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE).
  
    0.428
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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