| node1 | node2 | node1 annotation | node2 annotation | score |
| Deba_1225 | Deba_1290 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | 0.967 |
| Deba_1225 | Deba_1390 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | 0.708 |
| Deba_1225 | Deba_2480 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Anti-sigma-factor antagonist; InterPro IPR003658:IPR002645; KEGG: sfu:Sfum_1506 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: A0LIE3 Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor. | 0.837 |
| Deba_1225 | Deba_3182 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR004010:IPR003660:IPR010822:IPR001932; KEGG: dma:DMR_08680 putative phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C4XK04 Putative phosphatase; PFAM: HAMP domain; Cache domain; Stage II sporulation protein E (SpoIIE). | 0.708 |
| Deba_1290 | Deba_1225 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.967 |
| Deba_1290 | Deba_1390 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | 0.947 |
| Deba_1290 | Deba_1524 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: dth:DICTH_0761 anti-sigma regulatory factor; PFAM: ATP-binding region ATPase domain protein; SPTR: C1TN97 Anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.933 |
| Deba_1290 | Deba_2006 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: mem:Memar_2469 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: D1JH80 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.942 |
| Deba_1290 | Deba_2265 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR016196:IPR003594:IPR011701; KEGG: bbe:BBR47_11350 hypothetical protein; PFAM: major facilitator superfamily MFS_1; ATP-binding region ATPase domain protein; SPTR: C0Z6F5 Conserved hypothetical membrane protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Major Facilitator Superfamily. | 0.937 |
| Deba_1290 | Deba_2479 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | Protein of unknown function DUF534; COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851:IPR007487; KEGG: sfu:Sfum_1505 hypothetical protein; PFAM: protein of unknown function DUF534; inner-membrane translocator; SPTR: A0LIE2 Putative uncharacterized protein; PFAM: ABC transporter substrate binding protein; Branched-chain amino acid transport system / permease component. | 0.562 |
| Deba_1290 | Deba_2480 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | Anti-sigma-factor antagonist; InterPro IPR003658:IPR002645; KEGG: sfu:Sfum_1506 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: A0LIE3 Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor. | 0.939 |
| Deba_1290 | Deba_2858 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR018062; KEGG: pth:PTH_2271 xanthine/uracil permeases; PFAM: Xanthine/uracil/vitamin C permease; SPTR: A5CZY9 Xanthine/uracil permeases; PFAM: Permease family; TIGRFAM: uracil-xanthine permease. | 0.935 |
| Deba_1290 | Deba_3182 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR004010:IPR003660:IPR010822:IPR001932; KEGG: dma:DMR_08680 putative phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C4XK04 Putative phosphatase; PFAM: HAMP domain; Cache domain; Stage II sporulation protein E (SpoIIE). | 0.943 |
| Deba_1390 | Deba_1225 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.708 |
| Deba_1390 | Deba_1290 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...] | 0.947 |
| Deba_1390 | Deba_1524 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: dth:DICTH_0761 anti-sigma regulatory factor; PFAM: ATP-binding region ATPase domain protein; SPTR: C1TN97 Anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.644 |
| Deba_1390 | Deba_2006 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: mem:Memar_2469 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: D1JH80 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.918 |
| Deba_1390 | Deba_2265 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR016196:IPR003594:IPR011701; KEGG: bbe:BBR47_11350 hypothetical protein; PFAM: major facilitator superfamily MFS_1; ATP-binding region ATPase domain protein; SPTR: C0Z6F5 Conserved hypothetical membrane protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Major Facilitator Superfamily. | 0.646 |
| Deba_1390 | Deba_2479 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | Protein of unknown function DUF534; COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851:IPR007487; KEGG: sfu:Sfum_1505 hypothetical protein; PFAM: protein of unknown function DUF534; inner-membrane translocator; SPTR: A0LIE2 Putative uncharacterized protein; PFAM: ABC transporter substrate binding protein; Branched-chain amino acid transport system / permease component. | 0.408 |
| Deba_1390 | Deba_2480 | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: dae:Dtox_0924 protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C8W350 Protein serine/threonine phosphatase; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE). | Anti-sigma-factor antagonist; InterPro IPR003658:IPR002645; KEGG: sfu:Sfum_1506 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: A0LIE3 Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor. | 0.901 |