Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2542COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR004546:IPR002052:IPR003356:IPR002296; KEGG: dde:Dde_3429 type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Q30VS4 Type I restriction-modification system, M subunit; TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM). (505 aa)    
Predicted Functional Partners:
Deba_2538
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: dde:Dde_3425 restriction endonuclease S subunits-like; PFAM: restriction modification system DNA specificity domain; SPTR: Q30VS8 Restriction endonuclease S subunits-like; PFAM: Type I restriction modification DNA specificity domain.
 
 0.996
Deba_2537
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.979
Deba_2543
DNA binding domain protein, excisionase family; InterPro IPR010093:IPR009061; KEGG: dde:Dde_3430 putative transcriptional regulator; SPTR: Q30VS3 Putative transcriptional regulator; TIGRFAM: DNA binding domain protein, excisionase family; manually curated; TIGRFAM: DNA binding domain, excisionase family.
  
    0.804
Deba_2539
KEGG: cch:Cag_1524 DNA-damage-inducible protein D; SPTR: Q3AQE6 DNA-damage-inducible protein D.
       0.790
Deba_2541
KEGG: pca:Pcar_1481 hypothetical protein; SPTR: Q3A4I0 Putative uncharacterized protein.
       0.783
Deba_2540
Site-specific DNA-methyltransferase (adenine-specific); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002052:IPR003356:IPR002296; KEGG: dde:Dde_3427 type I restriction-modification system methylation subunit-like; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Q30VS6 Type I restriction-modification system methylation subunit-like; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM).
 
    
0.782
Deba_2534
Conserved hypothetical protein; COGs: COG3943 Virulence protein; KEGG: mmw:Mmwyl1_4371 hypothetical protein; SPTR: A6W3I7 Putative uncharacterized protein.
  
    0.739
Deba_2535
COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; InterPro IPR011335; KEGG: xcc:XCC2095 DNA helicase related protein; SPTR: Q8P8Y4 DNA helicase related protein; PFAM: Protein of unknown function (DUF3320).
  
  
 0.714
Deba_2030
COGs: COG1715 Restriction endonuclease; InterPro IPR007560; KEGG: ava:Ava_B0091 restriction endonuclease; PFAM: restriction endonuclease; SPTR: Q3M2I3 Restriction endonuclease; PFAM: Restriction endonuclease.
 
  
 0.604
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.494
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.